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微创经皮肾镜取石术中肾盂内压变化对术后发热的影响 被引量:99

Character and significance of renal pelvic pressure in minimally invasive percutaneous nephrolithotomy
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摘要 目的探讨微创经皮肾镜取石术(MPCNL)术中肾盂内压变化对术后发热的影响。方法采用压力传感器实时测量80例MPCNL手术患者肾盂内压,采用Logistic回归分析统计肾盂内压等因素变化与术后发热的关系。结果80例患者术中平均肾盂内压14.72mmHg(1mmHg=0.133kPa),肾盂内压≥30mrnHg平均累积时间为116.06S,术后出现体温≥38.5℃者15例。Logistic回归分析显示,术后发热与性别(P:0.195)、年龄(P=0.641)、尿路感染(P=0.663)、术后血常规白细胞≥10×10^9/L(P=0.751)、术中肾盂内压曾≥40mmHg(P=0.662)不相关,而与感染性结石(P=0.000)、通道大小(P=0.029)、术中平均肾盂内压(P=0.036)、术中平均肾盂内压≥20mmHg(P=0.013)、肾盂内压≥30mmI-Ig时间(P=0.010)相关,术中肾盂内压≥30mmHg状态持续50S以上者术后发热率发生显著增高(P=0.024)。结论MPCNL术中肾盂内压总的趋势小于一般认为引起肾实质反流的极限(30mmHg)。术后发热与MPCNL导致的肾盂内压短暂性增高不相关,但肾盂内压≥30mmHg状态持续〉50S、总平均肾盂内压升高将引起术后发热发生率增高。 Objective To investigate the renal pelvic pressure(RPP) during minimally invasive percutaneous nephrolithotomy(MPCNL), and inspect its influence to postoperative fever. Methods The RPP was measured by baroceptor, and these data about pressure and postoperative fever were evaluated statistically. Results The mean RPP was 14.72 mm Hg, the mean accumulative time of RPP≥30 mm Hg was 116.06 s. Fifteen cases(18.75%)had a postoperative fever. Logistical analysis suggested that postoperative fever did not correlate to sex(P=0. 195), age(P=0. 641), urinary tract infection (P= 0. 663), white blood cell≥10 × 10^9/L in blood routine examination postoperatively (P= 0. 751), once an occurrence of RPP≥40 mm Hg(P = 0. 662), while infection calculi (P = 0. 000), percutaneous tract size(P:0. 029) , mean RPP(P=0. 036) ,mean RPP≥20 mm Hg(P=0. 013), ac cumulative time of RPP≥30 mm Hg(P=0. 010) and RPP≥30 mm Hg longer than 50 s(P=0. 024) contributed to postoperative fever. Conclusions Renal pelvic pressure generally remains lower than a level to back-flow (30 mm Hg) during MPCNL. A transient renal pelvic pressure≥30 mm Hg don't countribute to postoperative fever, while a temporary high pressure status(50 s)would had an accumu lated effect which means an enough back-flow to bring a fever.
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2008年第10期668-671,共4页 Chinese Journal of Urology
关键词 肾造口术 经皮 肾盂内压 发热 Nephrostomy, percutaneous Renal pelvic pressure Fever
作者简介 通信作者:钟文,Email:gzgyzhongwen@163.com.
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参考文献7

  • 1曾国华,钟文,李逊,陈文忠,何朝辉,何永忠,雷鸣,吴开俊.微创经皮肾穿刺取石术中肾盂内压变化的临床研究[J].中华泌尿外科杂志,2007,28(2):101-103. 被引量:155
  • 2Landman J, Venkatesh R, Ragab M, et al. Comparison of intrarenal pressure and irrigant flow during percutaneous nephroscopy with an indwelling ureteral catheter, ureteral occlusion balloon, and ureteral access sheath. Urology, 2002, 60: 584-587.
  • 3Troxel SA, Low RK. Renal intrapelvic pressure during percutaneous nephrolithotomy and its correlation with the development of postoperative fever. J Urol, 2002, 168: 1348-1351.
  • 4Zeng GH, Zhong W, Li X, et al. The influence of minimally invasive percutaneous nephrolithotomy on renal pelvic pressure in vivo. Surg Laparosc, Endosc Percutan Tech, 2007, 17: 307-310.
  • 5Shariei A, Akhavizadegan H, Aryanpoor A, et at. Frequency of post percutaneous nephrolithotomy fever and its contributing factors. BJU Int, 2004, 94: 270-271.
  • 6Mariappan P, Loong CW. Mid stream urine C&S test is a poor predictor of infected urine proximal to the obstructing ureteric stone or infected stones: a prospective clinical study.J Urol, 2004, 171: 2142-2145.
  • 7Dogan HS, Sahin A, Cetinkaya Y, et al. Antibiotic prophylaxis in percutaneous nephrolithotomy., prospective study in 81 patients. J Endourol, 2002, 16: 649-653.

二级参考文献8

  • 1Kukreja RA,Desai MR,Sabnis RB,et al.Fluid absorption during percutaneous nephrolithotomy:does it matter.J Endourol,2002,16:221-224.
  • 2Troxel SA,Low RK.Renal intrapelvic pressure during percutaneous nephrolithotomy and its correlation with the development of postoperative fever.J Urol,2002,168:1348-1351.
  • 3Landman J,Venkatesh R,Ragab M,et al.Comparison of intrarenal pressure and irrigant flow during percutaneous nephroscopy with an indwelling ureteral catheter,ureteral occlusion balloon,and ureteral access sheath.Urology,2002,60:584-587.
  • 4Shariei A,Akhavizadegan H,Arianpoor A,et al.Frequency of postpercutaneous nephrolithotomy fever and its contributing factors.BJU Int,2004,94:270-271.
  • 5Dogan HS,Sahin A,Cetinkaya Y,et al.Antibiotic prophylaxis in percutaneous nephrolithotomy:prospective study in 81 patients.J Endourol,2002,16:649-653.
  • 6Stenberg A,Bohman SO,Morsing P,et al.Back-leak of pelvic urine to the bloodstream.Acta Physiol Scand,1988,134:223-234.
  • 7李逊.微创经皮肾穿刺取石术(MPCNL)[J].中国现代手术学杂志,2003,7(5):338-344. 被引量:290
  • 8李逊,曾国华,袁坚,吴开俊,单炽昌,郭彬,梁志雄.经皮肾穿刺取石术治疗上尿路结石(20年经验)[J].北京大学学报(医学版),2004,36(2):124-126. 被引量:491

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