摘要
目的:探讨实际屈伸和意想屈伸膝关节的脑功能生理机制。方法:通过血氧水平依赖性磁共振脑功能成像(BOLD-fMRI)技术研究8例正常志愿者分别实际屈伸和意想屈伸单侧膝关节时脑激活的情况,通过SPM5图像处理软件处理脑功能磁共振成像资料。结果:实际屈伸单侧膝关节时,对侧旁中央小叶、对侧辅助运动区、右侧颞上回及两侧顶下小叶明显激活;意想屈伸单侧膝关节时,对侧辅助运动区、对侧顶下小叶有明显激活,旁中央小叶未见激活;意想屈伸或实际屈伸单侧膝关节都未见基底核区激活。结论:对侧顶下小叶和对侧辅助运动区参与构成意想屈伸膝关节的中枢神经网络,基底核区可能不参与构成实际屈伸和意想屈伸膝关节的中枢神经网络。
Objective：To explore the physiology mechanism of neurological function in executing and imagining unilateral knee flexion-extension. Method： Eight healthy volunteers executed and imagined unilateral sequential knee flexion-extension, and the activation pattern of cortex was showed with functional magnetic resonance imaging （fMRI）.Image data were analysed by microsoft SPM5. Result：When subjects were executing unilateral knee flexion- extension, contralateral paracentral lobe and contralateral supplementary area and fight temporal gyrus and both sides of inferior parietal lobes were significantly activated. When subjects were imagining unilateral knee flexion- extension, significant activations were observed in contralateral supplementary area and contralateral inferior parietal lobe,but paracentral lobe was not activated during imagining unilateral knee flexion-extension. Basal ganglia were not activated during executing or imagining unilateral knee flexion-extension.Conclusion： The neural network of imaging knee flexion-extension involved contralateral inferior parietal lobe and contralateral supplementary motor area, while basal ganglia might not be involved.
出处
《中国康复医学杂志》
CAS
CSCD
北大核心
2008年第7期598-600,648,I0001,共5页
Chinese Journal of Rehabilitation Medicine
基金
上海市闸北区卫生局科研课题(2006重点05)
复旦大学附属华山医院院级课题资助
关键词
运动意想
膝关节屈伸
功能磁共振成像
motor imagery
knee flexion-extension
functional magnetic resonance imaging
作者简介
吴军发：男，硕士，主治医师。
通讯作者：吴毅 复旦大学附属华山医院康复医学科，wuyi3000@yahoo.com.cn
