摘要
肝纤维化是慢性肝病、肝硬化的共同病理基础.鉴于我国属HBV感染高流行区,HCV及其他病因引致的肝病也渐呈增高趋势,对HBV、HCV引起的肝病目前尚乏特效的清除病毒措施,肝病过程中由细胞因子和肝星状细胞(HSC)引发起的"瀑布式"效应也不因原始致病因子的清除而停止.因此,应提高对肝纤维化防治的认识并逐渐探索出一套防治肝纤维化的基本对策并规范实施.本文浅析目前肝纤维防治中的一些误区,指出防治肝纤维化的必要性及紧迫性.
Hepatic fibrosis is a common pathological ba- sis of chronic liver disease and liver cirrhosis. HBV infection is highly prevalent in China and there is an increasing trend of liver disease caused by HCV and other factors. However, no specific virus-eradicating drugs have been available for liver diseases caused by HBV and HCV. Cytokine-triggered and HSC-triggered waterfall effect does not cease with removal of the original pathogenic factor. Therefore, we should raise the awareness of prevention and treatment of hepatic fibrosis and gradually develop a set of basic countermeasures against hepatic fibrosis and standardize its implementation. This paper highlighted some misunderstandings in current prevention and treatment of hepatic fibrosis, and pointed out the necessity and urgency of prevention and treatment of liver fibrosis.
出处
《世界华人消化杂志》
CAS
北大核心
2008年第17期1833-1836,共4页
World Chinese Journal of Digestology
关键词
肝纤维化
防治
细胞因子
肝星状细胞
Liver fibrosis
Prevention and therapy
Cycokines
Hepatic stellate cell
作者简介
苌新明．教授，主任医师，主要从事慢性肝病防治研究 通讯作者：苌新明，710061．陕西省西安市健康路1号．西安交通大学医学院第一附属医院消化内科．cxm218@163.com 电话：029—85323924
