摘要
近年来研究发现,他汀类药物不仅具有降脂作用,而且在急性冠状动脉综合征中还具有抗炎作用。阿托伐他汀作为新一代他汀类新药在调节免疫抑制炎症方面具有更好的疗效,在阻止动脉硬化的发生、发展过程中,以及在急性冠状动脉综合征预防、早期治疗、后期延缓终末事件的发生中有明显的治疗效果,这种抗炎作用是独立于降脂作用之外的,其临床应用剂量国内外差异较大,应注意合理应用。
Recent studies showed that atorvastatin not only has effect decreasing lipid, but also has antiinflammatory effect in acute coronary syndrome. As a new generation of the statins, atorvastatin has the better curative effect on the regulation of immunity and inhibition of inflammation, it also has significant curative effect in inhibiting the genesis and development of atherosclerosis, preventing acute coronary syndrome, treating this disease early and postponing the advanced cases of this desease. Its anti-inflammatory effect can independent to its effect of lipid-decreasing. We should pay more attention to its rational usage because of great difference about its clinical dosage in domestic and abroad.
出处
《医学综述》
2008年第12期1888-1890,共3页
Medical Recapitulate
关键词
急性冠状动脉综合征
阿托伐他汀
抗炎作用
临床应用
Acute coronary syndrome
Atorvastatin
Anti-inflammatory effect
Clinical application
