摘要
目的探讨医院呼吸内科感染产AmpC酶阴沟肠杆菌的耐药性。方法对2001年1月-2006年12月,医院临床分离的阴沟肠杆菌364株(其中呼吸内科162株)进行了病区分布、感染部位及药敏结果调查;并用三维试验检测AmpC酶。结果162株呼吸内科分离的阴沟肠杆菌中产AmpC酶76株,产AmpC酶率为46.9%;而非呼吸内科分离的202株阴沟肠杆菌中产AmpC酶36株,产AmpC酶率为17.8%;且呼吸内科阴沟肠杆菌的耐药率明显高于非呼吸科科室。结论呼吸内科产AmpC酶阴沟肠杆菌的分离率和耐药率均高,应采取有效措施,遏制该菌引起的医院感染。
OBJECTIVE To investigate the drug-resistance of AmpC enzyme derepressing Enterobacter cloacae isolated from patients of respiratory department. METHODS Totally 364 strains of E. cloacae （162 strains from respiration department） collected from Jan 2001 to Dec 2006 were investigated to know their ward distribution, infection site and susceptibility test results. Three-dimensional tests were adopted to test AmpC lactamase. RESULTS Among the total 162 strains from respiration department, AmpC producers were 76 strains, accounting for 46.91%. Among the 202 strains from the other departments, however, AmpC producers were 36 strains, accounting for 17.82 %. And drug-resistance of E. cloacae from respiration department was distinctly higher than that from the other departments. CONCLUSIONS E. cloacae from respiratory department has the higher isolating rate and drug-resistance rate. We should take effective measurement to contain nosocomial infections with E. cloacae.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2008年第5期724-726,共3页
Chinese Journal of Nosocomiology
关键词
呼吸内科
医院感染
阴沟肠杆菌
产AMPC酶
耐药性
Respiratory department
Nosocomial infections
Enterobacter cloacae
Derepressed AmpC enzyme
Drug resistance
