摘要
目的建立可靠的鉴别和含量测定方法,以控制八正丸的质量。方法采用薄层色谱法鉴别大黄、栀子和甘草;采用高效液相色谱法测定样品中栀子苷的含量。结果薄层鉴别专属性强,高效液相色谱法测得栀子苷在0.1872～2.8080ng范围内呈良好的线性关系(r=0.9999),平均回收率100.70%,RSD为1.01%。结论该法简便、重复性好,可用于八正丸的质量控制。
Objective To establish the quality standard for Bazheng Pills. Methods Radix et Rhizoma Rhei, Radix Glycyrrhizae and Fructus Gardeniae in Bazheng Pills were identified by TLC. Geniposide was determined by HPLC. Results Radix et Rhizoma Rhei, Radix Glycyrrhizae and Fructus Gardeniae could be identified by TLC. Geniposide showed a good linear relationship at a range of 0. 187 2 - 2. 808 0 ng, r = 0. 999 9. The average recovery was 100. 70 % , and RSD was 1.01%. Conclusion The established methods are simple and with good reproducibility, and can be used for the quality control of Bazheng Pills.
出处
《中药新药与临床药理》
CAS
CSCD
2008年第2期140-142,145,共4页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
八正丸
栀子苷
质量标准
Bazheng Pills
Geniposide
Quality standard
作者简介
彭绍忠（1983-），男，2006级硕士研究生，主要从事中药新药开发研究。Email：pse8815@yahoo．com．cn。
通迅作者：苏子仁，研究员．Email：suziren@126．com.
