摘要
目的通过观察五苓散加减联合激光治疗中心性浆液性脉络膜视网膜病变的疗效,探讨五苓散加减在激光治疗中心性浆液性脉络膜视网膜病变围手术期中的作用。方法对中心性浆液性脉络膜视网膜病变患者57例60只眼,按随机原则分组治疗,治疗组(激光联合中药组)28例30只眼用五苓散加减配合激光光凝治疗;对照组(单纯激光组)29例30只眼用单纯激光治疗,观察两组疗效。结果①两组患者均经激光治疗1周后视力明显提高,但1周及6周时组间比较差异均无显著性(P>0.05);②治疗1个月后两组患者视网膜水肿及渗出吸收、中心视野10°总灰度值、P-VEP潜时比较均有统计学意义(P<0.05);P-VEP振幅比较无统计学意义。③治疗1个月两组总体疗效分别是90%、80%,两组比较有统计学意义。治疗6周后总体疗效比较无统计学意义。结论在本病激光围手术期中用五苓散加减可以更快促进视网膜渗液吸收,缩短病程,改善视功能。
OBJECTIVE To investigate the efficiency of the Chinese medicine （modified Wuling Powder） in the perioperational period by evaluating clinical effectiveness of combined therapy of central serous chorioretinopathy （CSC） with Chinese medicine and laser photocoagulation. METHODS Sixty eyes of 57 cases of CSC were randomly allocated into different therapeutic groups. There were 30 eyes of 28 cases in the combined therapy group （Group A）, treated with modified Wuling powder together with laser photocoagulation. Thirty eyes of 29 cases were in the control group （ Group B）, treated simply with laser photocoagulation. Comparison of the clinical therapeutic effects of these 2 groups was made. RESULTS （1） A week after therapy, significant improvement of visual acuity was found, but no significant difference of visual acuity was found between Group A and B （ P 〉 0.05）. （2） A month after therapy,retina edema was assimilated respectively in both groups,showing statistical difference （P 〈 0.05）.Improvement of the total grayscale within 10 degrees of the visual field, the delitescence of P - VEP were marked significant difference between group A and B. （3） A month after treatment, the overall effectiveness of group A and B was 90 % and 80 % respectively, showing statistical difference （ P 〈 0.05）. But 6 weeks after treatment, it showed no statistical difference （ P 〉 0.05）. CONCLUSIONS The Chinese medicine used in treatment of this disease during peri - operational period could facilitate retinal edema absorption, shorten the course of the disease, make less damage of the cone cells, and so to visual function improvement.
出处
《中国中医眼科杂志》
2008年第1期16-18,共3页
China Journal of Chinese Ophthalmology
