摘要
采用不同的给药方式对环丙沙星(CPFX)在模拟水生态系统中的归趋进行研究,包括环丙沙星在水体、沉积物、生物体(皇冠草、河蚬、异育银鲫)等不同分配相及生物体不同组织、器官中的含量、分布以及迁移、富集等动态变化过程。结果表明:CPFX进入模拟水生态系统后,水体中药物浓度下降迅速,3种给药方式下,最高浓度不超过15.30μg.L-1。底泥表现出明显的吸附积累,而且长时间地保持高浓度残留;在饲料给药方式下,底泥药物浓度最高可达2379.67μg.L-1。水生生物对CPFX有不同程度的富集和残留,水草对CPFX的吸收较多,尤其是叶片部分,药物浓度最高可达899.83μg.L-1;河蚬、鱼体对CPFX有一定的吸收积累,停药15d后,河蚬、鱼体内仍有明显的残留,不同组织对CPFX的吸收积累存在显著差别,在内脏中的积累量比肌肉组织高。3种给药方式导致的鱼体内药物残留量大小依次是:饲料给药>混合给药>水体给药。
The distribution, accumulation and transfer dynamics of Ciprofloxacin（CPFX） in water, sediments and biota in a simulated micro-cosmos system using different exposure techniques were studied. In addition to photodegradation, some CPFX released into water was assimilated by aquatic organisms and some was deposited in the sediments. The concentration of CPFX in water decreased rapidly, and the highest concentration is less than 15. 301μg·L^-1 from the three exposure techniques. CPFX was adsorbed and accumulated in the sediments and could maintain at high concentration up to 2379. 67μg·L^-1 with feed administration. There were differences in the distribution, accumulation and transfer dynamics of CPFX in different aquatic organisms： water seed Echinodorus amazonicus adsorbed CPFX mainly by its leaf instead of its roots and the highest concentration was found to be 899. 83μg·L^-1; carp Allogynogenetic crucian and clam Corbicula fluminea had the ability to accumulate CPFX, which could stay in the tissue of organisms for a long time. Significant differences of CPFX bioaccumulation between the viscera and the muscle were observed, and higher concentration of CPFX was found in the former tissue. The bioaccumulations of CPFX in Allogynogenetic crucian carp were shown to be different using different exposure techniques with the following order： feed administration 〉 mixed administration 〉 water administration.
出处
《生态学报》
CAS
CSCD
北大核心
2007年第12期5300-5307,共8页
Acta Ecologica Sinica
基金
国家自然科学基金资助项目(40471118)~~
作者简介
陈菊芳（1970-），女，福建邵武人，副研究员，从事水域生态学研究．E-mail：chenjufang116@163．com
