摘要
目的：对毛莲蒿的化学成分进行研究。方法：采用硅胶和聚酰胺柱层析进行分离，运用红外光谱、紫外光谱、质谱、核磁共振谱与标准品对照的方法鉴定１５个化合物。结果：分离鉴定了３个倍半萜类：ｔａｕｒｉｎ（１）、１，１１ｂｉｓｅｐｉａｒｔｅｓｉｎ（２）、ｙｏｍｏｇｉｎ（３）；３个黄酮类：５，７，３′，４′四羟基６，８二甲氧基黄酮（４）、５，７，３′，４′四羟基６甲氧基黄酮（５）、５，６，３′，４′四羟基７甲氧基黄酮（６）；３个三萜类：蒲公英赛醇乙酸酯（７）、木栓酮（８）、α香树脂醇（９）；２个甾体类：β谷甾醇（１０）、胡萝卜苷（１１），２个香豆素类：莨菪亭（１２）、７羟基６，８二甲氧基香豆素（１３）；２个有机酸类：异阿魏酸（１４）、咖啡酸（１５）。
OBJECTIVE: To study the chemical constituents of Artemisia vestita. METHODS: The chemical constituents of Artemisia vestita were isolated with silica gel and polyamide chromatography and their structures were identified by means of IR, UV, MS, 1 H NMR, 13 C NMR and DEPT, in some cases by direct comparison with authentic samples. RESULTS: Fifteen compounds were obtained and identified as taurin (1), 1, 11 bis epi artesin (2), yomogin (3), 5, 7, 3′, 4′ tetrahydroxy 6, 8 dimethoxy flavone (4), 5, 7, 3′, 4′ tetrahydroxy 6 methoxy flavone (5), 5, 6, 3′, 4′ tetrahydroxy 7 methoxy flavone (6), taraxerol 3β acetate (7), friedelin (8), α amyrin (9), β sitosterol (10), daucosterol (11), scoplatin (12), 7 hydroxy 6, 8 dimethoxy coumarin (13), isoferulic acid (14), caffeic acid (15). CONCLUSION: All these compounds were isolated from this plant for the first time.
出处
《中国药学杂志》
EI
CAS
CSCD
北大核心
1997年第8期462-465,共4页
Chinese Pharmaceutical Journal
关键词
毛莲蒿
倍半萜
黄酮
香豆素
化学成分
Artemisia vestita, sesquiterpenoids, flavonoids, coumarins
