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自发性腹膜炎对慢性重型肝炎预后的影响 被引量:7

The influence of spontaneous peritonitis on the prognosis of chronic severe hepatitis
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摘要 目的探讨自发性腹膜炎临床表现及其对慢性重型肝炎患者预后的影响。方法对某院2003年3月—2006年10月收住院的104例慢性重型肝炎患者,按是否并发自发性腹膜炎分为腹膜炎组48例,对照组56例,比较两组住院天数、治愈率、病死率等。结果腹膜炎组患者主要临床表现为腹胀(87.50%)、发热(72.92%)、腹部压痛(70.83%)及反跳痛(52.08%)、腹肌紧张(50.00%)等;腹腔积液白细胞计数>0.3×109/L者44例(91.66%),中性粒细胞比值>0.25者46例(95.83%);腹腔积液细菌培养仅6例(12.50%)阳性。腹膜炎组患者住院时间为(51.70±5.62)d,治愈率为18.75%,病死率为58.33%;对照组分别为(36.30±6.36)d、41.07%、25.00%;上述两组各项两两比较,差异均有显著性(分别P<0.01、P<0.05、P<0.01)。结论自发性腹膜炎对慢性重型肝炎预后有明显不良影响。 Objective To evaluate clinical manifestations and influence of spontaneous peritonitis on the prognosis of chronic severe hepatitis. Methods According to whether patients had spontaneous peritonitis, 104 chronic severe hepatitis patients hospitalized from March 2003 to October 2006 were divided into peritonitis group (48 cases) and control group (56 cases), the duration of hospital stay, the curing rate and mortality between two groups of patients were compared. Results In the peritonitis group, the main clinical manifestations were abdominal distention (87. 50%), fever(72. 92%), abdominal tenderness(70.83%), rebound tenderness (52. 08%), abdominal muscle tension (50. 00%), et al ; 44 (91.66%) patients' ascites white blood cell count were 〉0. 3 × 10^9/L, 46 (95.83%) patients ascites neutrophilic granulocyte ratio were 〉0. 25; only 6 patients (12. 50%) had positive bacterial culture of ascites; the hospitalization days, curing rate and mortality in peritonitis group were (51. 70 ± 5. 62) days, 18. 75% and 58. 33% respectively; and in control group were (36. 30 ± 6. 36) days, 41.07% and 25.00% respectively, there were significant difference respectively between two groups (P〈0. 01, P〈0. 05, P〈0. 01 ;respectively). Conclusion Spontaneous peritonitis has obvious bad influence on the prognosis of chronic severe hepatitis.
出处 《中国感染控制杂志》 CAS 2007年第6期384-386,共3页 Chinese Journal of Infection Control
关键词 自发性腹膜炎 重型肝炎 腹腔积液 治疗结果 spontaneous hepatitis severe hepatitis ascites treatment result
作者简介 通讯作者:陶志广(1962-),男(汉旅),湖南省株洲市人,主治医师,主要从事传染病学研究。E-mail:Ta02629@163.com
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  • 1[1]Chang CS,Chen GH,Lien HC,et al.Small intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis.Hepatology,1998,11:28(5):1187-1190
  • 2[2]Lafond P,Viallon A,Zeni F,et al.Justification of routine puncture of ascites in cirrhotic patients admitted to emergency hospital units.Presse Med,1995,24(11):531-533
  • 3[3]Hughes WJ,Armstrong P,Bodey GP.Guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever.J Infect Dis,1990,161:381

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