摘要
目的 研究重型肝炎合并自发性细菌性腹膜炎（SBP）的临床特点和诊疗结果.方法 选择2010年3月～2012年3月泸州医学院附属医院诊疗的132例重型肝炎患者作为研究对象,72例患者经确诊合并SBP者为观察组,60例无SBP者为对照组,回顾性分析上述两组患者的临床资料,对SBP的临床特点和诊疗效果进行研究.结果 观察组患者的临床表现包括发热、腹痛、腹胀及腹部压痛;腹水常规检查显示观察组白细胞数为（9.86±2.84）×109/L,与对照组[（8.96±2.32）×109/L]比较,差异无统计学意义（P＞0.05）;观察组中性粒细胞比值为（0.77±0.18）,明显高于对照组（0.56±0.13）,差异有统计学意义（P＜0.05）;腹水细菌培养检查结果显示12例细菌阳性,其中大肠埃希菌5例,肺炎克雷伯杆菌3例,肺炎链球菌2例,葡萄糖球菌1例,1例为混合真菌感染.结论 重型肝炎合并SBP的临床表现缺乏特异性,致病菌类多样,腹水检查效果不佳,中性粒细胞的检测可为该并发症的早期诊断和治疗提供了依据.
Objective To discuss the clinical features and results for severe hepatitis combined with spontaneous bacterial peritonitis.Methods 132 cases of patients with severe hepatitis from March 2010 to March 2012 in Affiliated Hospital of Luzhou Medical College were selected as research object.72 patients of severe hepatitis combined with spontaneous bacterial peritonitis were divided into observation group; 60 cases of severe hepatitis without spontaneous bacterial peritonitis were divided into control group.The clinical data of these patients was analyzed retrospectively.The clinical features and results of spontaneous bacterial peritonitis were studied.Results Clinical manifestation were fever,abdominal pain,bloating and abdominal tenderness in observation group; white blood cell count in observation group was （9.86±2.84）×109/L,white blood cell count in control group was （8.96±2.32）×109/L,the difference was not statistically significant （P 〉 0.05）; the ratio of polymorphonuclear in observation group was （0.77±0.18）,it was higher than that in control group （0.56±0.13）,the differences were statistically significant （P 〈 0.05）.12 cases of positive bacteria were found including 5 cases of Escherichia coli,3 cases of Klebsiella pneumoniae,2 cases of Streptococcus pneumonia,1 case of Glucose cocci,1 case of mixed fungal infections.Conclusion Clinical manifestations of severe hepatitis combined with spontaneous bacterial peritonitis is lack of specific.The pathogenic bacteria types are varied,and the ascites examination results are poor.The detection of the polymorphonuclear can provide foundation for early diagnosis and treatment of complications.
出处
《中国医药导报》
CAS
2013年第35期8-10,共3页
China Medical Herald
基金
国家自然科学基金项目(编号81201282)
关键词
重型肝炎
自发性细菌性腹膜炎
病理诊断
传播特性
Severe hepatitis
Spontaneous bacterial peritonitis
Pathological diagnosis
Propagation characteristics
作者简介
吴刚（1967.1-）,男,博士,副主任医师.
