摘要
目的:研究黄芪多糖(APS)注射液对氢化考地松致免疫功能低下小鼠血清IL一4、IFN-γ的影响,探讨黄芪多糖注射液调节机体免疫功能的作用,为APS的临床应用提供实验依据。方法:ELISA法检测血清中IL-4及IFN-γ水平。结果:APS能够使免疫功能低下小鼠血清IFN-γ水平明显升高,而IL-4水平很低。结论:APS能够重建免疫功能低下机体正常的免疫功能,促进机体ThO向Thl分化,维持TH1,的优势状态,增强机体的细胞免疫功能。
Objective：To study the effect of RPS to IL-4,In-y in the hypoimmunity mice induced by hydrocortisone, to discuss its function of regulating the immune function, to provide the experiment basis for clinical practice of APS. Methods： the level of cytokine IFN - r and IL4 were detected by ELISA. Result： APS can raise the level of serum IFN - r obviously in hypoimmunity mice, and the level of IL - 4 was very low. Conclusion： APS can rebuild immune function of hypoimmuni ty mice, promoted organism ThO to split up to Thl, maintained the advantage state of TH1, strengthened the function of cellular mediated imrnunoresponse.
出处
《内蒙古中医药》
2007年第10期35-36,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
黄芪多糖(APS)
ELISA
细胞免疫
Astragalus Polysaccharide （APS）
EL ISA
cellular mediated imrnunoresponse
