摘要
研究西洋参多糖（ｐｏｌｙｓａｃｃｈａｒｉｄｅｆｒｏｍｐａｎａｘｑｕｉｎｑｕｅｆｏｌｉｕｍＰＰＱ）对小鼠脾淋巴细胞刺激效应。通过３Ｈ掺入法测淋巴细胞转化及母细胞增殖法测ＩＬ－２合成。结果表明，ＰＰＱ可协同亚剂量ＣｏｎＡ促进脾淋巴细胞转化及ＩＬ－２合成。将ＰＰＱ—１进一步分离得到４种成分（ＰＰＱ－１－１～４）。体外实验结果表明，ＰＰＱ－１－１～４既可单独也可协同亚剂量ＣｏｎＡ促进脾淋巴细胞转化。提示西洋参多糖对小鼠脾淋巴细胞具有一定刺激作用。
We studied the stimulating effect of PPQ on spleen lymphocyte of mice.The results show that PPQ can enhance lymphocyte transformation and IL-2 production induced by Con A in suboptimal concentration.Moreover,four refined components PPQ-1-1～4 can induce murine lymphocyte transformation with or without Con A in suboptimal concentration
出处
《白求恩医科大学学报》
CSCD
1997年第3期236-238,共3页
Journal of Norman Bethune University of Medical Science
基金
国家中医药管理局重点课题
关键词
西洋参多糖
多糖
淋巴细胞转化
白细胞介素
Polysaccharide from panax quinquefolium Lymphocyte transformation Interleukin 2
