摘要
目的观察医用几丁糖预防术后肠粘连的效果。方法2004年9月～2006年2月共143例病人行剖腹手术,随机分成试验组和对照组,试验组(72例)应用医用几丁糖预防术后肠粘连,对照组(71例)术后直接关腹。结果试验组经过至少6个月的随访无1例发生肠粘连,对照组出现10例肠粘连症状,3例严重者出现粘连性肠梗阻。结论医用几丁糖是一种较理想的预防术后肠粘连的生物材料。
[Objective] To explore the effect of chitosan on the prevention of postoperative peritoneal adhesion. [Methods] Since Sep. 2004 to Feb. 2006, 143 patients undergoing lapamtomy were allocated to ehitosan group and control group randomly. The patients in chitosan group （n =72） were injected ehitosan in abdominal cavity. The patients in control group （n =71） were closed up the incision without any prevention. [Results] All patients were followed up at least 6 months. None of the patients in ehitosan group suffered from bowel adhesion. 10 patients in control group suffered from bowel adhesion, and 3 of them underwent adhesive intestine obstruction. [Conclusions] Chitosan has significant clinical value in preventing postoperation intestinal adhesion.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2007年第13期1643-1644,1648,共3页
China Journal of Modern Medicine
关键词
医用几丁糖
肠粘连
预防
medical ehitosan
intestine adhesion
randomized comparison
prospectively
作者简介
[通讯作者]张阳德
