摘要
目的评价肝动脉化疗栓塞(TACE)结合三维适形放射治疗(3DCRT)对原发性肝癌(PHC)的效果。方法94例原发性肝癌患者进行前瞻性随机分组研究,综合治疗组48例进行TACE结合3DCRT治疗,对照组46例单纯行TACE治疗。结果1,2,3 a生存率综合治疗组分别为83%、62%、43%,对照组为52%、25%、15%,2组比较有显著性差异(P<0.05);2组毒副作用相似。结论TACE结合3DCRT治疗PHC能明显提高临床治疗效果,而毒副作用未见增加。
Objective It is to evaluate the effects of transcatheter arterial chemoembolization （TACE） combined with 3 - dimensional conformal radiation therapy （3DCRT） for unresectable primary hepatic carcinoma （PHC）. Methods 94 patients of PHC were prospectively randomized investigation. The control group （46 patients） with TACE therapy alone, and the combined group （48 patients） with the therapy of TACE combined with 3DCRT. Results The overall first year, scend year, third year survival rate was 83%, 62%, 43% in the combined group. It was 52%, 25%, 15% in the control group. The difference between the two groups was significant （ P 〈 0.05 ）. But the difference of treatment-related toxicities between these two groups was not significant （P〉0.05）. Conduaion TACE combined with 3DCRT is an effective and feasible approach with minimal trauma in the treatment of PHC.
出处
《现代中西医结合杂志》
CAS
2007年第12期1600-1601,共2页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
原发性肝癌
化学栓塞
三维适形放射疗法
primary hepatic carcinoma
chemoembolization
3- dimensional conformal radiation therapy
作者简介
蔡春梅（1973-），女，主治医师，主要从事临床放射治疗及研究工作。
