摘要
目的:研究盐酸纳洛酮在失水和吸收水分的过程中引起晶型的变化。方法:采用红外光谱、热重分析及 X-射线粉末衍射法研究盐酸纳洛酮晶型变化特征。结果:发现盐酸纳洛酮存在2种结晶型和1种无定型。结论:在不同的试验条件下,盐酸纳洛酮的晶型会发生相互转化。
Objective：To study the polymorphic form transformation of naloxone hydrochloride induced by losing and absorbing the water. Method： Using FTIR, TGA and X - ray powder diffraction to research the various polymorphic forms. Result： Naloxone hydrochloride exsited in two types of polymorphic form and one amorphous form in this study. Conclusion：Under the different experimentation condition,the polymorphic form and amorphous form of naloxone hydrochloride can transfer one another.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2007年第2期169-170,共2页
Chinese Journal of Pharmaceutical Analysis
作者简介
Tel：（010）67095655；E—mail：zyj95860@yahoo．com．cn
