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原发性肝癌多层螺旋CT灌注成像临床研究 被引量:7

The Study of Multidetector CT Perfusion in Primary Liver Carcinoma
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摘要 目的:探讨原发性肝癌多层螺旋CT灌注成像的价值。方法:采用PHILIPS16层螺旋CT对23例原发性肝癌及13例无肝脏疾病患者进行肝脏灌注扫描,并用其ExtendedBrillianceTM工作站灌注软件分别测量肝动脉灌注量、肝门静脉灌注量、总肝灌注量及肝动脉灌注指数等,以评价原发性肝癌的血流动力学改变及其规律性。结果:原发性肝癌组肝动脉灌注量、肝门静脉灌注量、总肝灌注量和肝动脉灌注指数分别为0·45±0·26ml·min-1·ml-1、0·31±0·22ml·min-1·ml-1、0·76±0·34ml·min-1·ml-1和0·61±0·21;对照组分别为0·19±0·06ml·min-1·ml-1、0·66±0·20ml·min-1·ml-1、0·86±0·20ml·min-1·ml-1和0·23±0·08。与对照组比较,原发性肝癌的组肝动脉灌注量和肝动脉灌注指数显著增高,肝门静脉灌注量显著降低,总肝灌注量稍降低,但差异无统计学意义。结论:原发性肝癌与正常肝脏CT血流灌注参数肝动脉灌注量、肝门静脉灌注量和肝动脉灌注指数存在显著差异;CT灌注成像可用于评价原发性肝癌血流灌注情况。 Objective: To study the parameters of CT perfusion imaging of primary, liver carcinoma (PIE). Methods: CT perfusion imaging of liver was obtained in 36 individuals, including 23 patients with PLC and 13 control subjects. Liver perfusion parameters such as hepatic arterial perfusion (HAP), hepatic portal peffuiosn (HPP), total liver perfusion (TLP) and hepatic arterial perffusion index (HAPI) were calculated, and the change of the hemodynamics was estimated. Results: Compared with the control group, HAP ( 0.45 ± 0.26ml· min^- 1· ml^- 1 versus 0.19 ± 0.06ml·min^- 1· ml^-1, P = 0.001 ) and HAPI ( 0.61 ± 0.21 versus 0.23 ± 0.08, P = 0.000) in PLC group increased significantly, HPP (0.31 ± 0.22 ml·min^-1·ml^-1 versus 0.66± 0.20ml· min^-1·ml^-1, P = 0.003 ) decreased significantly, TLP (0.76 ± 0.34ml· min^-1· ml^-1 versus 0.86 ± 0.20ml·min^- 1· ml^- 1, P = 0.329) did not differ between the two groups. Conclusion: CT perfusion imaging could be a new method to ewduate the blood supply of PLC.
出处 《华西医学》 CAS 2006年第4期705-706,共2页 West China Medical Journal
关键词 多层CT 腺发性肝癌 灌注成像 multidetector CT primary liver carcinoma peffusion imaging
作者简介 杨林(1965-),男,四川广安人,主治医师,在读博士研究生. 通讯作者
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参考文献16

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二级参考文献42

  • 1李家平,杨建勇,江利,陈伟.运用CT动态灌注成像技术测定肝脏血流量的临床研究[J].临床放射学杂志,2005,24(2):130-134. 被引量:25
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