摘要
目的了解白求恩国际和平医院临床分离的鲍曼不动杆菌临床感染分布和耐药现状。方法收集2002年1月至2004年12月白求恩国际和平医院鲍曼不动杆菌临床分离株,采用Kirby-Bauer法对19种抗菌药物进行药敏试验;用WHONET 5分析试验结果;分析感染患者基础疾病特征。结果3年间共分离鲍曼不动杆菌267株,96.25%分离自住院患者,3.75%分离自门诊患者。该菌对亚胺培南高度敏感,对其他药物呈多重耐药。多重耐药菌株在逐年上升。它主要引起住院老年人和严重外伤患者的下呼吸道感染。结论鲍曼不动杆菌耐药性有逐年上升趋势。
Objective To determine the disrtibution and resistance of clincal isolates ot Acinetobacter baurnannil from Bethune International Peace Hospital. Methods The collection of clinical strains of Acinetobacter baumannii isolated from Bethune International Peace Hospital were completed. The bacterial susceptibility to 19 kinds of antimicrobial agents were determined by Kirby-Bauer method. The results were analyzed with Whonet 5 soft ware. And the basic disease feature of the infected patients was analyzed. Results 267 strains were isolated during 3 years. 96.25% of them isolated from inpatients, 3.75% from outpatients. Most of them were susceptible to imipenem, and resistant to the other antimicrobial agents tested to a great extend. Multidrug resistant strains were increasing year by year. Majority of the isolates caused lower respiratory tract infection of older inpatients and serious wounded ones. Conclusion The drug-resistant rate of Acinetobacterbaumannii isolates was showing a tendancy to increase year by year.
出处
《中国微生态学杂志》
CAS
CSCD
2006年第4期310-311,314,共3页
Chinese Journal of Microecology
基金
河北省科技攻关计划项目(04276184)
关键词
鲍曼不动杆菌
感染
药物耐药性
Acinetobacter baumannii
Infection
Drug-resistance
作者简介
侯天文(1967-),男,硕士,副主任技师,从事细菌耐药机制研究