摘要
烟酰胺是一种抗氧化剂,它能有效地预防细胞和细胞膜免去自由基的损伤,可消除炎症中起作用的超氧阴离子自由基。评价外用烟酰胺的抗炎作用、改善皮肤角质层屏障及润肤作用、减少皮肤色素沉着作用、改善面部皮肤衰老表现以及预防光免疫抑制和光致癌作用。目前的研究提示,外用烟酰胺制剂在皮肤科有广泛的应用前景,值得开发。
Nicotinamide, an antioxidant, can efficiently protect cells and cell membrane from damage by free radicals and scavenge super-oxide radical（O2） participating in inflammatory process. We review topical application of nicotinamide in some skin diseases and its mechanism of action, including anti-inflammatory properties, improvements in the barrier of stratum comeum and in aging facial skin appearance, moisturizing effects, reduction of pigmentation, prevention of photoimmunosuppression and photocarcinogenesis. The current research hints topical nicotinamide product has a broad application foreground in dermatological field and is worthy of exploitation.
出处
《国际皮肤性病学杂志》
2006年第3期142-143,共2页
International Journal of Dermatology and Venereology
关键词
烟酰胺
生物医学研究
皮肤疾病
Nicotinamide
Biomedical research
Skin diseases
