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抗肿瘤新药伊立替康的合成和应用进展 被引量:7

Advancement in the Synthesis and Clinical Application of the New Anticancer Drug Irinotecan
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摘要 抗肿瘤新药伊立替康是一种可溶性喜树碱类衍生物,就伊立替康的合成、作用机制、构效关系、临床应用及毒副作用等方面的研究进展进行了综述。 The new anticancer drug Irinotecan is one of the soluble derivatives of campothecin. We made a summary of the advancement in the synthesis, anticancer mechanism, structure-activity relationship, clinical application and toxicity of Irinotecan in this paper.
出处 《淮海工学院学报(自然科学版)》 CAS 2005年第4期42-45,51,共5页 Journal of Huaihai Institute of Technology:Natural Sciences Edition
关键词 伊立替康 合成 综述 Irinotecan synthesis summary
作者简介 刘玮炜(1965-).女.江苏滨海人,淮海工学院化学工程系教授,博士,主要从事有机合成方面的研究,(E-mail)liuww323@yahoo.com.cn。
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