摘要
目的:探讨急性脑梗死患者血清脂蛋白(a)[Lp(a)]与血小板活化率的相关性。方法:采用免疫比浊法测定血清Lp(a),流式细胞术检测血小板活化标志物CD62P,电阻抗法计数血小板,对77例急性脑梗死患者和50例健康体检者进行了检测。结果:急性脑梗死患者血清Lp(a),血浆CD62P检测结果均值均显著高于对照组,并呈显著正相关;血小板计数与对照组相比差异无显著性。结论:血清Lp(a)直接激活血小板可能是其促血栓形成的重要机制之一。为急性脑梗死及血栓性疾病的诊断、预后及疗效评估提供了实验依据。
Objective To investigate relationship between the level of Lp（a） in plasma and the status of Platelets activation in patientd with acute cerebral infarction. Methods 77 patients and 50 normal subjects were studied. The serum level of Lp（a） was tested quantitatively by turbidimetry,CD62P was detected by flow eytometry （FCM）,and Platelets were counted by impedance method. Results The serum level of Lp （a） and the positive rates of CD62P in patients with acute cerebral infarction were significantly higher than those in control group, and they were significantly ralative. The counts of Platelets in patients With acute cerebral infarctionwas significantly decreased. Conclusion Lp （a） actived PLT directedly perhaps is one of important mechanisms of making acute cerebral infaretionand other thrombus diseases.
出处
《实用医技杂志》
2005年第11A期3036-3038,共3页
Journal of Practical Medical Techniques
作者简介
赵金霞（1974-），女，山东东明人，1997年毕业于青岛大学医学院，主管检验师。
