摘要
本文用~3HTdR掺入法及双抗体夹心ELISA法测定了69例急性和慢性乙型肝炎病人的淋巴细胞转化功能(淋转)和血清可溶性白细胞介素2受体(SIL-2R)的变化。结果显示患者淋巴细胞在体外经ConA刺激后的转化和增殖功能明显低于正常人。乙肝病人血清SIL-2R水平均显著升高,其中急性肝炎和慢活肝较慢迁肝升高更为明显。血清ALT水平高低与HBV标志物和ALT有密切关系。提示急、慢性乙肝病人均存在淋巴细胞功能障碍,血清SIL-2R检测可望做为观察病程、临床诊断分型及判断疗效的指标。
We have measured function of lyphocyte transform and serum soluble interleukin 2 receptor (sIL-2R) of patients with acute and chronic hepatitis B with method of ③3H TdR joined and ELISAThe results showed function of lymphocyte transform of hepatitis B stimulated by Con-A are lower markerly than that of the normal controls. The levels of sIL-2R of these patients are higher significant than the controls Activities of ALT of the patients are related with levels of sIL-2R. It is suggested that function of lymphocyte transform of patients infected with HBV are reduced, Measurement of resum sIL-2R would be a newparamement for estimation of damage of liver and determination curative effect.
出处
《临床肝胆病杂志》
CAS
1995年第2期75-77,共3页
Journal of Clinical Hepatology
