摘要
应用彩色多普勒血流显像技术监测了３１例妊高征孕妇及７４例正常孕妇子宫胎盘血流，同时测定血中雌三醇（Ｅ＿３）、胎盘泌乳素（ｈＰＬ）、血栓素代谢产物（ＴＸＢ＿２）、前列环素代谢产物（６－ＫＰ）及ＴＸＢ＿２／６－ＫＰ比值。结果表明：正常孕妇子宫动脉及胎儿脐动脉的时间平均血流速度（ＴＡＶ）及血流量（Ｑ）明显高于妊高征孕妇（Ｐ＜０．０５）。妊高征孕妇经用硫酸镁及青心酮治疗后，子宫胎盘血液循环明显改善，子宫动脉及脐动脉ＴＡＶ及Ｑ均增加（Ｐ＜０．０５）。正常孕妇血中Ｅ＿３及ｈＰＬ浓度明显高于妊高征孕妇。妊高征孕妇的ＴＸＢ＿２／６－ＫＰ比值明显高于正常孕妇。提示：ＴＡＶ及Ｑ可直接反映子宫胎盘血液灌注情况，对了解胎盘功能及估计胎儿预后具有实际应用价值。
he uteroplacental blood flow was monitored using color Doppler flow imaging(CDFI)in 31 cases of pregnancy induced hypertension(PIH)and 71 cases of normal pregnancy. At the same time the values of serum estriol(E_3),human placental lactogen (hPL), thromboxane(TXB_2),6-KP and TXB_2/6-KP ratio were measured. The results showed that time average velocity(TAV)and voiume of blood flow(Q)of uterine and umbilical arteries in PIH cases were much lower than those in normal pregnant women and fetuses(P< 0. 05 ).After treatment with magnesium sulfate and qingxintong there was a marked improvement in placental blood flow. TAV and Q of uterine and umbilical arteries was also in-creased(P<0. 05).In PIH cases the E_3 and hPL levels were much lower,while the ratio ofTXB_2/6-KP was significantly higher than that in normal pregnancy,Using CDFI to observe the velocity and vol-ume of uteroplacental blood flow can monitor the blood supply of uterus and placenta. It is a valuable predictive index of fetal and placental function.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1995年第6期337-339,共3页
Chinese Journal of Obstetrics and Gynecology
基金
国家自然科学基金
关键词
妊娠高血压
综合征
胎盘
脐动脉
血流
超声波诊
Ultrasonics Pregnancy induced hypertension Placenta Umbilical artery
