摘要
目的探讨多房囊性肾细胞癌患者手术治疗的预后特点. 方法回顾性分析482例肾癌患者中22例多房囊性肾细胞癌患者资料,分析其手术治疗的预后特点.多房囊性肾细胞癌占同期肾癌病例的4.56%,男女比例为2.67:1.00,年龄32～74岁,平均47岁. 结果 22例患者中行肾癌根治术18例,行肾部分切除术4例.肿瘤直径1.8～11.0 cm,平均4.8 cm.其中透明细胞癌21例,透明细胞癌与颗粒细胞癌混合型1例;pT1N0M0 19例,pT2N0M0 2例;pT3bN0M0 1例;G1 5例,G2 17例.失访2例,20例获随访,随访时间9～56个月,平均27.6个月.其中1例因肝硬化、上消化道出血死亡,无瘤存活21例. 结论多房囊性肾癌是肾癌的一种特殊类型,多为肾偶发癌,病理分期分级低,预后与肿瘤大小无关,手术治疗效果满意,预后佳.
Objective To evaluate the prognosis of surgery in multilocular cystic renal cell carcinoma (MCRCC). Methods The characteristics of prognosis of surgery in 22 MCRCC cases out of 482 cases of renal cell carcinoma were reviewed.The MCRCC cases accounted for 4.56% of the renal cell carcinoma cases with a male-to-female ratio of 2.67∶1 in the same period.The mean age of the 22 patients was 47 years (age range,32-74 years). Results Of the 22 cases,18 underwent radical nephrectomy and 4 partial nephrectomy.The diameter of the tumors ranged 1.8-11.0 cm (mean 4.8 cm).Histological examination showed that 21 cases were of clear cell carcinoma and 1 of clear cell carcinoma mixed with granular cell carcinoma.Pathological staging showed pT 1N 0M 0 in 19 cases (86.4%),pT 2N 0M 0 in 2(9.1%) and pT 3bN 0M 0 in 1(4.5%).The classification by tumor nuclear grading system showed 5 cases (23%) of G 1 and 17 (77%) of G 2.Twenty patients were followed up for 9-56 months (mean,27.6 months) and 2 were lost of follow-up.Of the 20 patients,19 survived with no evidence of cancer and 1 died of intercurrent disease (upper gastrointestinal massive hemorrhage due to hepatocirrhosis). Conclusions MCRCC represents a distinct subtype of renal cell carcinoma.It is usually with low grade,low stage and is found incidentally.Our results indicate that MCRCC can be cured by surgery.Regardless of tumor size,the prognosis of MCRCC is favorable.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2005年第4期253-255,共3页
Chinese Journal of Urology
关键词
多房囊性肾细胞癌
外科手术
治疗
预后
Kidney neoplasms
Carcinoma
Multilocular cystic
Nephrectomy
Prognosis
