摘要
合成了叠氮苄、对氰基叠氮苄,对氟叠氮苄,对甲基叠氮苄和联苯二叠氮苄,研究了苯环上不同取代基对苄基卤代物与叠氮化钠经亲核取代反应生成苄基叠氮化物的反应的影响。苄基对位上吸电子基团的存在,可以促使反应较容易进行,而供电子基团的存在,会降低反应的速度。
Azides, such as benzylazide, p-cyanoazide, p-fluo-roazide, p-methylazide and biphenylazide, were synthesized via the reaction of benzyl chloride or substituted benzyl chloride and sodium azide.The effects of substituents on the nucleophilic reaction of benzyl halide and sodium azide were studied. Benzene bearing an electron withdrawing substituent on the para position of benzyl group underwent the reaction much faster; while an electron releasing substituent on the same position reduced the reaction rate.
出处
《化学试剂》
CAS
CSCD
北大核心
2005年第1期39-40,共2页
Chemical Reagents
基金
国家高技术发展计划(863计划课题编号2002AA305103)
武器装备基金项目(项目编号:51412020103QT3111)的资助.
关键词
取代基
叠氮化物
合成
substituents
azides
synthesis
