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糖耐量受损患者血清可溶性E选择素和血管细胞黏附分子1的水平 被引量:3

Serum levels of soluble E-selectin and vascular cell adhesion molecule-1 in patients with impaired glucose tolerance
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摘要  用ELISA法测定 62例糖耐量受损(IGT)患者、24名正常糖耐量 (NGT)者和 23例 2型糖尿病患者可溶性E选择素和可溶性血管细胞黏附分子 1(sVCAM 1)的血清水平,发现IGT患者sVCAM 1浓度明显高于NGT者,提示IGT患者已发生不同程度的血管内皮细胞功能障碍。 The serum levels of soluble E selectin (sE selectin) and soluble vascular cell adhesion molecule 1 (sVCAM 1) were determined by ELISA in impaired glucose tolerance (IGT) group (62 cases), normal glucose tolerance (NGT) group (24 subjects), and diabetes mellitus group (23 cases). Serum sVCAM 1 level in the IGT group was significantly higher than that in the NGT group (P<0.01). It suggests that an early endothelial dysfunction to various extents is present in the patients with IGT.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2005年第1期29-30,共2页 Chinese Journal of Endocrinology and Metabolism
关键词 患者 可溶性E选择素 糖耐量受损 血管细胞 黏附分子 IGT SVCAM-1 水平 发现 Impaired glucose tolerance E-selectin Vascular cell adhesion molecule-1 Endothelial dysfunction
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参考文献5

  • 1牛小燕,朱本章,姚孝礼,杨玉.E-选择素与糖尿病视网膜病变相关性的研究[J].中华内分泌代谢杂志,2004,20(6):538-539. 被引量:3
  • 2徐茂锦,邹大进,叶江洪,冯正康,张小瑛.抗氧化维生素降低2型糖尿病患者血清可溶性血管细胞粘附分子1水平[J].中华内分泌代谢杂志,2003,19(2):119-121. 被引量:3
  • 3Sengoelge G, Fodinger M, Skoupy S, et al. Endothelial cell adhesion molecule and PMNL response to inflammatory stimuli and AGE-modified fibroncetin. Kidney Int, 1998,54:1637-1651.
  • 4Matsumoto K, Miyake S, Yano M, et al. High serum concentrations of soluble E-selectin in patients with impaired glucose tolerance with hyperinsulinemia. Atherosclerosis, 2000,152:415-420.
  • 5Dogruel N, Kirel B, Akgun Y, et al. Serum soluble endothelial-cell specific adhesion molecules in children with insulin-dependent diabetes mellitus. J Pediatr Endocrinol Metab, 2001,14:287-293.

二级参考文献15

  • 1Blann AD, Lip GY. Cell adhesion molecules in cardiovascular disease and its risk factor-what can soluble levels tell us? J Clin Endocrinol Metab, 2000,85:1745-1747.
  • 2Albertini JP, Valensi P, Lormeau B, et al. Elevated concentrations of soluble E-selectin and vascular cell adhesion molecule-1 in NIDDM.Effect of intensive insulin treatment. Diabetes Care, 1998,21: 1008-1013.
  • 3Lu M, Perez VL, MaN, etal. VEGF increases retinal vascularICAM-1expression in vivo. Invest Ophthalmol Vis Sci, 1999,40:1808-1812.
  • 4Olson JA, Whitelaw CM, Mchardy KC,et al,Soluable leucocyte adhesion molecules in diabetic retinopathy stimulate retinal capillary endothelial cell migration. Diabetologia, 1997,40:1166-1171.
  • 5Quehenberger P;Bierhaus A;Fasching P.Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells[J],2000(9).
  • 6Fasching P;Voitl M;Rohac M.Elevated concentrations of circulating adhesion molecules and their association with microvascular complication in insulin-dependent diabetes mellitus[J],1996.
  • 7De Mattia G;Bravi MC;Laurenti O.Reduction of oxidative stress by oral N-acetyl-L-cysteine treatment decreases plamsa soluble vascular cell adhesion molecule-1 concentrations in non-obese,non-dyslipidemic,normotensive patients with non-insulin-dependent diabetes[J],1998.
  • 8Jager A;Van Hinsbergh VW;Kostense PJ.Increased levels of soluble vascular cell adhesion molecule 1 are associated with risk of cardiovascular mortality in type 2 diabetes:the Hoom study[J],2000.
  • 9Ceriello A;Giugliano D;Quatraro A.A preliminary note on inhibiting effect of α-tocopherol (Vitamin E) on protein glycation,1988(14).
  • 10Svoboda P;Stolba P;Hegenbartova M.The mechanism of lowing or nonenzymatic glycation by Vitamin C,1992.

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