期刊文献+

微量白蛋白尿与冠脉狭窄程度相关性研究 被引量:9

Study on the Correlation Between Microalbuminuria and Severity of Coronary Constriction
在线阅读 下载PDF
导出
摘要 【目的】研究微量白蛋白尿与冠心病的关系。【方法】按冠状动脉造影诊断标准将 4 2例患者分为冠心病组 (15人 )与非冠心病组 (2 7人 ) ,测定晨尿白蛋白 /肌酐浓度值 (ACR) ,比较两组患者尿ACR并分析ACR与冠脉病变程度的相关性。【结果】冠心病组ACR为 (138.4 9± 99.4 0 ) μg/mg显著高于非冠心病组的(5 3.83± 4 9.83) μg/mg ;ACR与冠脉计分呈显著的直线正相关 ;ACR正常组和ACR升高组危险因素个数及冠心病发病率相比差异均有显著性。【结论】检测ACR ,可能可以识别冠心病高危患者 ,并可能反映冠脉病变的严重程度。 To investigate the relationship between microalbuminuria and coronary artery disease(CAD).According to the diagnostic standard of coronary artery angiography, forty-two patients were divided into CAD group(15 patients) and non-CAD group (27 patients). The albumin and creatinine concentration ratio (ACR) in morning urine samples from patients of both groups was estimated and compared. The correlation of ACR to the extent of coronary lesions was analyzed.ACR in the CAD group(138.49±99.40)was significantly higher than that in non-CAD group(53.83±49.83). A distinctly linear positive correlation existed between ACR and the score of the coronary lesions ; when the number of risk factors and occurrence rate of CAD were compared between the patients with elevated ACR and those with normal ACR, the mutual difference showed statistical significance.[Conclusion]Detection of ACR may recognize patients with high risk of CAD and possibly reflect the severity of coronary lesions.
出处 《医学临床研究》 CAS 2004年第5期492-494,共3页 Journal of Clinical Research
关键词 冠状动脉疾病 白蛋白尿 coronary disease albuminuria
  • 相关文献

参考文献7

  • 1Hoehner CM,Greenlund KJ,Rith-Najarian S,et al .Association of the insulin resistance syndrome and microalbuminuria among nondiabetic native Americans.The Iner-Tribal Heart Project[J].J Am Soc Nephrol ,2002,13:1626-1634.
  • 2Hans l,Hillege,Vaclav Fidler,et al .Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population[J].Circulation ,2002,106:1777-1782.
  • 3Borch-Johnsen K,Feldt-Rasmussen B,Strandgaard S,et al .Urinary albumin excretion:an independent predictor of ischemic heart disease [J].Arteriosclerosis,Thrombosis,and Vascular Biology ,1999,19:1992-1997.
  • 4Gokmen SS,Kilicli G,Ozcelik F,et al .Association between serum total and lipid-bound sialic acid concentration and the severity of coronary atherosclerosis[J].J Lab Clin Med ,2002,140(2):110-118.
  • 5Diercks GF,Van Boven AJ,Hillege HL,et al.Microalbuminuria is independently associated with ischaemic electrocardiographic abnormalities in a large non diabetic population[J].Eur Heart J ,2000,21:1922-1927.
  • 6Clausen P,Jensen JS,Jensen G,et al .Elevated urinary albumin excretion is associated with impaired arterial dilatory capacity in clinically healthy subjects [J].Circulation ,2001,103:1869-1874.
  • 7周翔海,纪立农.尿白蛋白肌酐比与UAER相关性分析[J].辽宁实用糖尿病杂志,2001,9(3):23-25. 被引量:12

二级参考文献7

  • 1[1]Mattock MB, Keen H, Viberti GC, et al. Coronary heart disease and urinary albumin excretion rate in type 2(non-insulin dependent)diabetic patients. Diabetologia 1988 ;31:82.
  • 2[2]Deckert T, Yokoyama H, Mathiesen E, et al. Cohort study of predictive value of urinary albumin excretion for atherosclerotic vascular disease in patients with insulin dependent diabetes. BMJ 1996; 312: 871.
  • 3[3]Damsgaard EM, Froland A, Jorgensen OD. Microalbuminuria as predictor of increased mortality in elderly people. BMJ 1990; 300: 297.
  • 4[4]American Diabetes Associaton: Consensus development conference on the diagnosis and management of nephropathy in patients with diabetes mellitus ( Consensus Statement). Diabetes Care 1994; 17:1357.
  • 5[5]Cundy TF, Nixon D, Berkahn L, et al. Measuring the albumin excretion rate: agreement between methods and biological variability. Diabet Med 1992;9:138.
  • 6[6]Mogensen CE, Keane WF, Bennett PH, et al. Prevention of diabetic renal disease with spectial reference to microalbuminuria. Lancet 1995;346:1080.
  • 7[7]Ng WY, Lui KF, Thai AC. Evaluation of a rapid screening testfor microalbuminuria with a spot measurement of urine albumin- creatinine ratio. Ann Acad Med Singapore 2000;29:62.

共引文献11

同被引文献77

引证文献9

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部