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乳腺疾病患者发生乳腺癌的危险因素分析 被引量:16

Risk factors of breast cancer in the patents with breast diseases
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摘要 目的:回顾性调查乳腺疾病患者的自然状况与乳腺癌发病关系的内在联系,并分析其影响因素。方法:以1981-01/2001-12在茂名市人民医院以乳腺疾病来求治的36000例患者作为对象,采用统一设计的回顾性调查表,用存档的病例资料填写,然后录入电脑,利用数据库进行筛选,并运用SAS6.12软件进行统计学分析。结果:患乳腺疾病15100例(41.944%)。其中乳腺增生14400例(40.000%);纤维瘤692例1.922%);乳腺癌8例0.022%)。分析结((果为:文化程度高、体质量指数大、精神心理压抑、有女性生殖系统疾病史、摄入乳类食品多,为主要危险因数,可增加发病危险性。而常吃葱等食物及避孕年数多为保护性因子。结论:高危人群中文化程度高、体质量指数大、长期精神压抑、患女性生殖系统疾病者,长期高脂饮食与乳腺增生、乳腺纤维瘤及乳腺癌发生的内在联系较密切,发病率较高。 AIM:To retrospectively investigate the intrinsic correlation between natural s tatus of patients with breast diseases and the attack of breast cancer,and analy ze the factors that influence the latter. METHODS:Totally 36 000 females who asked for treatment because of their breast diseases in Maoshan Municipal People's Hospital from January 1981 to November 2 001 were chosen as the subjects.The subjects were asked to fill in the filed cas e data using the uniformly designed retrospective questionnaire,and then the cas e data were input into a computer.Then,the data was screened by using data base followed by statistical analysis with ASA 6.12 software. RESULTS: The were 15 100 cases of breast diseases(41.944%) out of the 36 000 subjects,including 14 400 cases hyperplasia of mammary glands(40.000%),692 case s of fibroadenoma(1.922%) and 8 cases of breast cancer(0.022%).As shown in the analysis for the results,the major risk factors that could increase the risk of attack were high level education,high index of body mass,psychic and mental de pression,the history of female reproductive system diseases and much intake of d airy products.Comparatively,eating shallot very often and many years' contracept ion were the protective factors. CONCLUSION:For the high risk female group,long term intake of high fat diet in those who were with high level education,high index of body mass,long term mental depression or the history of female reproductive system diseases,is of cl ose internal correlation with the attack of hyperplasia of mammary glands,fibroa denoma and breast cancer in a high incidence rate.
出处 《中国临床康复》 CSCD 北大核心 2005年第2期158-159,共2页 Chinese Journal of Clinical Rehabilitation
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