摘要
目的 :探讨氯沙坦联合福辛普利治疗慢性充血性心力衰竭 (CHF)的临床疗效。方法 :82例CHF患者随机分成治疗组和对照组。治疗组40例给予氯沙坦50mg/d ,福辛普利10mg/d ,对照组给予福辛普利10mg/d ,及安慰剂治疗。两组基础治疗类同 ,疗程6个月。观察治疗前后两组患者的临床症状 ,超声心动图心功能指标 ,6分钟步行距离的变化及不良反应。结果 :两组治疗前后相比左室射血分数 (LVEF)、6分钟步行距离均有显著改善 (P<0.01〉 ,治疗组LVEF及6分钟步行距离的发送优于对照组。结论 :氯沙坦联合福辛普利治疗CHF可以增强疗效。
Objective:To evaluate the clinical therapeutic efficacy of losartan combined with fosinopril on the treatment of congestive heart failure(CHF).Methods:Using random and single blind contrast during the period of month,we divided82patients with CHF into the treatment group(n=40)and the control group(n=42),The clinical therapeutic efficacy,LVEF,6min walk trial and adverse reactions were anaˉlyzed.Results:The clinical prognosis and LVEF,6min walk tril of the patient in the two group were all significantly ameliorated compared with those of the patient before treatment(P<0.01).Improvement of symptom in treatment group was better than that in control group.Conclusion:losartan combined with fosinopril has obvious effects on treating patient with CHF.
出处
《现代医药卫生》
2005年第4期387-388,共2页
Journal of Modern Medicine & Health
