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黄精赞育胶囊优选方对弱精子症大鼠精子运动能力的影响 被引量:13

Effects of Huangjignzanyu Optimized Formula on Sperm Motility in Rat with Asthenospermia
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摘要 目的 :研究黄精赞育胶囊优选方对弱精子症大鼠精子运动能力的影响。方法 :采用雷公藤多甙制备大鼠弱精子症模型 ,通过计算机辅助精子分析系统 (CASA)观察黄精赞育胶囊优选方对精子运动速度和运动方式的影响。结果 :优选方中剂量组可显著提高精子密度、活力、活率及运动速度 (VCL、VSL、VAP)。其疗效与黄精赞育组相似 ,且优于大剂量、小剂量和五子衍宗丸组 ,而优选方三种剂量对精子运动方式 (LIN、STR、WOB、ALH、BCF、MAD)均无显著改善。结论 :黄精赞育胶囊优选方具有提高精子密度、活力、活率及运动速度的作用。 Objective :To study the effects of Huangjingzanyu optimized formula on sperm motility in rat with asthenospermia. Methods :Rats with asthenospermia were induced by Multiglycosides of Tripterygium Wilfordii(GTW).Sperm motility velocity and motility mode were measured with computer-aidd sperm analysis(CASA). Results :Sperm concentration,motility,viability and motility velocity(VCL、VSL、VAP)were significantly increased in middle dosage of optimized formula.The effects of middle dosage group were similar to those of Huangjingzanyu group and better than those of large dosage,small dosage and wuziyangzong pill group.Sperm motility mode(LIN、STR、WOB、ALH、BCF、MAD)were not changed significantly in 3 different dosage of optimized formula. Conclusions :Huangjingzanyu optimized formula can increase sperm concentration,motility,viability and motility velocity.
出处 《中医药学刊》 2005年第2期368-369,383,共3页 Study Journal of Traditional Chinese Medicine
关键词 黄精赞育胶囊优选方 雷公藤多甙 精子运动能力 Huangjingzanyu optimized formula Multiglycosides of Tripterygium Wilfordii(GTW) sperm motility
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