摘要
目的 为了解海口地区超广谱 β 内酰胺酶 (ESBLs)阳性菌的种类及其分布 ,为控制其扩散、预防暴发流行提供科学依据。方法 采用双纸片琼脂扩散法 ,测定 3年中从临床各类标本分离的革兰阴性菌的ESBLs ,比较菌种、病房及标本间ESBLs阳性率差异。结果 产ESBLs的菌种已达 2 8种 ,阳性率最高达 6 0 % ,常见菌的阳性率均达约 5 0 % ,且 3年间的变化多数无统计学意义 ;ESBLs阳性菌分离率在病室间的差异不大 ,门诊患者相对住院患者较低 ,在标本间的分布存在一定差异。结论 ESBLs阳性菌已在海口地区广泛存在 ,并已成为医院及社区感染的主要病原菌 ,控制其进一步发展已成为一项迫在眉睫的工作。
OBJECTIVE To detect the ESBLS + bacteria and find out their distribution in the ward of hospital and social environment of Haikou city, and supply some scientific data for controlling and preventing the expanding of ESBLs + bacteria and the breaking out of infection with it in clinics. METHODS Using double-disc agar diffusion, we detected the ESBLs of Gram negative bacteria which isolated from all samples in 2000-2002 at Haikou area and analyzed the diffrence of ESBLs positive rate among the bacteria,samples, and wards. RESULTS The ESBLs + bacteria were 28 kinds. The highest ESBLs positive-rate of bacteria was 60%, most of them were about 50%; there were no significant changes among the wards during the three years; the ESBLs + rate of bacteria isolated from out-patients was lower than that from in-patients and there were some differences among the samples. CONCLUSIONS The ESBLs + bacteria exist in Haikou area at a high level and also are the main pathogeny. To control and prevent the ESBLs + bacteria expansion and the breaking out of their infection it in clinics are urged for us.
出处
《中华医院感染学杂志》
CAS
CSCD
2004年第8期932-935,共4页
Chinese Journal of Nosocomiology
基金
海南省卫生厅科研基金资助项目 (琼卫 2 0 0 0 84 )
关键词
ESBLS
海口地区
流行病学
Extended spectrum β-lactamases
Haikou area
Epidemiology
