摘要
用辣根过氧化物酶逆行标记法结合免疫细胞化学法(PAP法)对大鼠迷走神经背核尾侧部内神经降压肽样免疫反应终末的核内联系进行了电镜下的研究.发现少量神经降压肽样免疫反应轴突终末与HRP逆行标记的副交感节前神经元的树突构成非对称性突触;大多数神经降压肽样免疫反应轴突终末与未标记中间神经元的胞体和树突构成对称性或非对称性突触,以轴-树突触为主;未标记的轴突终末也可同HRP逆行标记的副交感节前神经元的胞体和树突构成对称性或非对称性突触.由此认为核内神经降压肽样免疫反应终末可通过直接或间接联系(后者为主)作用于副交感节前神经元,从而参与对内脏、心血管活动的调节.
In order to approach the morphological basis for the visceral and cardiovascular effects produced by central administration of neurotensin,the synaptic connections of neurotensin-like immunoreactive (NT-LI) terminals in the caudal portion of the dorsal vagal nucleus were studied by means of the retrograde labeled horse radish peroxidase (HRP) method and immunoelectron microscopic PAP technique.The results showed that a few NT-LI axonal terminals formed asymmetrical synapses with HRP retrograde labeled dendrites of the parasympathetic preganglionic neurons,and the majority of them formed symmetrical and asymetrical synapses with unlabeled dendrites and soma of the intermediate neurons,most of them being the axo-dendritic synapses.Symetrical and asymmetrical synapses also existed between unlabeled axonal terminals and HRP retrograde labeled dendrites or soma of the parasympathetic preganglionic neurons.These findings indicated that NT-LI terminals in the dorsal vagal nucleus affected the parasympathetic preganglionic neurons by direct and indirect synaptic connections to regulate visceral and cardiovascular activities.
出处
《解剖学杂志》
CAS
CSCD
北大核心
1993年第5期437-440,共4页
Chinese Journal of Anatomy
关键词
迷走神经背核
神经降压肽
免疫电镜
dorsal vagal nucleus
neurotensin
immunoelectron microscopy
synaptic connection
