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创伤弧菌感染的致病机制研究现状 被引量:8

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摘要 创伤弧菌是弧菌属低度嗜盐菌,自然生存于近海和海湾的海水和海底沉积物中[1].国外有关创伤弧菌感染的临床报道以及研究逐渐增多,然而,在国内对创伤弧菌感染脓毒血症病例报道不多.创伤弧菌可通过进食生的牡蛎穿过胃肠道黏膜或通过破损的皮肤接触海水入血而感染,并在短时间内出现败血症和蜂窝组织炎、出血性大疱,几天内病人便出现感染性休克直至死亡,死亡率高达70%[2].因其病情凶险,引起了国内外学者的关注并对其致病机制做了较多研究.本文主要对其临床表现以及致病机制做一总结和探讨.
作者 吴斌 卢中秋
出处 《中国急救医学》 CAS CSCD 北大核心 2004年第11期834-835,共2页 Chinese Journal of Critical Care Medicine
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参考文献20

  • 1Pfeffer CS, Hite MF, Oliver JD. Ecology of Vibrio vulnificus in Estuarine Waters of Eastern North Carolina[J]. Appl Environ Microbiol, 2003, 69(6) :3526-3531.
  • 2Moscola 1. Vibrio vulnificus infections associated with raw oyster-Los Angeles[J]. MMWR, 1996,45(29) :621-622.
  • 3Klontz KC, Lieb S, Schreiber M, et al. Syndromes of Vibrio vulnificus infections. Clinical and epidemiologic features in Florida cases, 1981-1987[J]. Ann Intern Med, 1988,109(4) :318-323.
  • 4Oliver JD, Wear JE, Thomas MB, et al. Production of extracellular enzymes and cytotoxicity by Vibrio vulnificus[J]. Diagn Microbiol Infect Dis, 1986,5(2) :99-111.
  • 5Miyoshi S, Kawata K,Tomochika K, et al. The hemagglutinating action of Vibrio vulnificus metalloprotease[J]. Microbiol Immunol, 1999,43 ( 1 ): 79-82.
  • 6Miyoshi S. Effects of Vibrio vulnificus metalloprotease on the capillaries:pathological actions and inactivation by alpha-macroglobulin [J].Yakugaku Zasshi,2000,120(11): 1149-1157.
  • 7Miyoshi S, Kawata K, et al. The C-terminal domain promotes the hemorrhagic damage caused by Vibrio vulnificus metalloprotease [J].Toxicon,2001,39(12): 1883-1886.
  • 8Miyoshi S, Narukawa H, Tomochika K, et al. Actions of Vibrio vulnificus metalloprotease on human plasma proteinase-proteinase inhibitor systems: a comparative study of native protease with its derivative modified by polyethylene glycol[J]. Microbiol Immun
  • 9Fan JJ, Shao CP, Ho YC, et al. Isolation and characterization of a Vibrio vulnificus mutant deficient in both extracellular metalloprotease and cytolysin[J]. Infect Immun,2001,69(9) :5943-5948.
  • 10Shao CP, Hor, LI.Metalloprotease is not essential for Vibrio vulnificus virulence in mice[J]. Infect Immun,2000,68(6):3569-3573.

二级参考文献42

  • 1陈通,张子强,尹利佳,朱有法,石元和,沈祥骥.大肠癌超微结构的观察[J].实用肿瘤杂志,1989,4(2):84-87. 被引量:4
  • 2易平勇,杨光华,谭永淑,李甘地.大肠腺癌的核形态定量分析及其在临床病理上的意义[J].中华病理学杂志,1994,23(3):141-143. 被引量:7
  • 3陈柯,螘国铮,胡闻,涂景林.大肠癌酶细胞化学及电镜观察[J].肿瘤防治研究,1995,22(4):218-221. 被引量:3
  • 4张浩波,郁宝铭.大肠癌及其癌前病变定量形态学研究[J].上海医学,1995,18(12):686-689. 被引量:5
  • 5姜红.原发性创伤弧菌败血症1例[J].中华内科杂志,1991,(10):645-645.
  • 6Nakafusa J, Misago N, Miura Y, et al. The importance of serum creatine phosiahokinase level in the early diagnosis, and as a prognostic factor, of Vibrio vulnificus infection[J]. Br J Dennatol, 2001,145(2) :280 - 284.
  • 7Chang JJ, Sheen IS, Peng SM, et al. Vibrio vulnificus infection - report of 8 cases and review of cases[J]. Changgeng Yi Xue Za Zhi, 1994,17(4) :339-346.
  • 8Hlady WG, Mullen RC, Hopkin RS. Vibrio vulnificus from raw oysters.Leading cause of reported deaths from foodborne illness in Florida[J] .J Fla Med Assoc, 1993,80(8) : 536 - 538.
  • 9Lerstloomapleephunt N, Tantawichien T, Sitprija V. Renal failure in Vibrio vulnificus infection[J]. Ren Fail,2000,22(3) :337 - 343.
  • 10Ali A,Mehra MR, Stapleton DD, et al.Vibrio vulnificus sepsis in solid organ transplantation: a medical nemesis [ J ]. J Heart Lung Transplant,1995,14(3) :598 - 600.

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