摘要
目的 评价吸入丙酸氟替卡松和二丙酸倍氯米松治疗儿童哮喘的疗效。方法 选取 2 0 0 3年 1-2月初诊时使用丙酸氟替卡松的 >6岁二级哮喘患儿 2 0例为治疗组 ,选取 2 0 0 0年初诊时使用二丙酸倍氯米松的 >6岁哮喘患儿 2 0例为对照组 ,两组均在初诊时及治疗第 3、6、9、12月详细记录其哮喘发作次数、吸入β2 受体激动剂的次数以及呼气峰流速 (PEFR)值。统计分析以上两组数据。结果 初诊时两组患儿的发作次数及吸入 β2 受体激动剂的次数无差异 (P >0 .0 5 ) ,在治疗第 3、6、9、12月两组差异有非常显著性 (P <0 .0 1) ,在增加PEER值、改善肺功能方面 ,两组在治疗 3月后差异有非常显著性 (P <0 .0 1) ,在治疗第 6、9、12月后差异有显著性 (P <0 .0 5 ) ,结论 吸入丙酸氟替卡松治疗儿童哮喘较吸入二丙酸倍氯米松效果更好且安全。
Objective To evaluate the efficacy of fluticasone propionate and beclomethasone dipropionate inhalation in treating children asthma.Methods Choice twenty asthmatic children of >6 years who were treated with fluticasone propionate in January and February 2003,with the children as the treat group;Choice twenty asthmatic children of >6 years who were treated with beclomethasone dipropionate in 2000,with the children as the control group. Before the treatment 3、6、9、12months after the treatment, the frequency of asthma happening、the frequency of inhale β 2- receptor agonist、peak expiratory flow rate(PEFR) were carefully recorded in 2 groups. Statistical analyse the data of 2 groups.Results Before treatment, the frequency of asthma happening and the frequency of inhale β 2- receptor agonist have no defferent between 2 groups(P>0.05),3、6、9、12months after treatment, the data of treat group were significantly different from the control group(P<0.01),3months after treatment, the improved PEFR of the treat group were significantly different from the control group (P<0. 01);6、9、12months after treatment, the improved PEFR of treat group were different from the control group(P<0.05).Conclusions Fluticasone propionate inhalation for treating children asthma is more effective and safer than beclomethasone dipropionate.
出处
《海南医学》
CAS
2004年第10期30-31,共2页
Hainan Medical Journal
关键词
丙酸氟替卡松
二丙酸倍氯米松
儿童
哮喘
皮质激素吸入
Fluticasone propionate
Beclomethasone Dipropionate
Children
Asthma
Gorticosteroids inhalation
