摘要
目的测量并评价慢性乙型肝炎患者生活质量,分析其主要影响因素。方法采用健康调查简易表(SF-36),对200例慢性乙型肝炎患者及200例正常对照进行生活质量测量,并对生活质量的影响因素进行单因素分析和多因素逐步回归分析,寻找其中主要影响因素。结果慢性乙型肝炎患者组的SF-36总评分及生理机能、角色生理状况、心理健康状况、社会功能、机体活力、躯体不适和主观健康状况的平均评分与对照组相比显著降低(P均<0.01);影响慢性乙肝患者生活质量的主要因素是病程、并发症、谷丙转氨酶、乏力、黄疽。结论慢性乙型肝炎患者的生活质量全面下降,有效的治疗以缩短病程、减少并发症及心理治疗和护理将有利于改善患者的生活质量。
AIM:To measure the quality of life(QOL) of patients with chronic hepatitis B and analyse the main influencing factors.METHODS:QOL of 200 patients with chronic hepatitis B and 200 healthy controls subjects were tested by health investigation simply questionnaire(SF 36),and univariate analysis and multiple stepwise regression analysis were used to evaluate the main factors which affected QOL.RESULTS:The total score of SF 36 in the patients with chronic hepatitis B,and the average scores on physical function,physiological status,psychological health status,social mechanism,body activity,body malaise and subjective health status were significantly lower than those of the control group(all P< 0.01).The factors affecting QOL of patients with chronic hepatitis B were mainly duration of disease,complications, glutamic pyruvic transaminase,malaise and icterus.CONCLUSION:The QOL of patients with chronic hepatitis B declines universally.Effective treatment like shorter duration of disease,less complications,mental treatment and nursing can improve the QOL of patients.
出处
《中国临床康复》
CSCD
2004年第24期4960-4961,共2页
Chinese Journal of Clinical Rehabilitation