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14-3-3:保护性信号转导调节蛋白 被引量:4

14-3-3:protective regulatory protein in signaling transduction
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摘要   14 3 3蛋白家族是真核细胞中高度保守的可溶性蛋白。在哺乳动物 ,14 3 3蛋白主要存在于脑。 14 3 3蛋白与许多蛋白结合 ,在细胞凋亡、生长、增殖的信号转导过程中发挥关键的调节作用 ,是细胞内重要的保护性蛋白。 14 3 3蛋白还是一些脑疾病的诊断标志。 14 3
出处 《生理科学进展》 CAS CSCD 北大核心 2004年第3期247-250,共4页 Progress in Physiological Sciences
基金 国家自然科学基金 (30 2 70 4 2 6 ) 北京市自然科学基金(70 32 0 2 6 )资助课题
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  • 2Woodcock JM, Murphy J, Stomski FC, et al. The dimeric versus monomeric status of 14-3-3zeta is controlled by phosphorylation of Ser58 at the dimer interface. J Biol Chem,2003, 278: 36323-36327.
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