摘要
Epstain-Barr病毒(Epstain-Barr virus,EBV)是一种重要的肿瘤相关病毒,成人感染率超过90%。EB病毒与鼻咽癌、霍奇金和非霍奇金淋巴瘤、胃癌、移植后淋巴增生症等多种肿瘤的发生密切相关。本文介绍了EB病毒感染的实验室诊断方法及其临床应用,重点介绍了儿童常见非肿瘤性EB病毒感染疾病(传染性单核细胞增多症、慢性活动性EB病毒感染、EB病毒相关噬血淋巴组织细胞增生症)的临床特征、诊断指南及需要进一步研究的问题。
Epstain-Barr virus(EBV) is an important tumor-related virus,infects over 90% of the world s adult population.EBV is also associated with a wide variety of malignancies including nasopharyngeal carcinoma(NPC),Hodgkin and non-Hodgkin lymphomas,gastric carcinoma,post-transplant lymphoproliferative disorder(PTLD).This review introduced laboratory diagnostic assays of EBV infection,and focused on clinical feature and diagnostic guidline of non-malignant diseases associated with EBV infection in children(includin...
出处
《首都医科大学学报》
CAS
北大核心
2010年第2期213-216,共4页
Journal of Capital Medical University
基金
首都医学发展基金(编号2007-2062)资助项目~~
关键词
EB病毒
传染性单核细胞增多症
慢性活动性EB病毒感染
EB病毒相关噬血淋巴组织细胞增生症
儿童
Epstain-Barr virus
infectious mononucleosis
chronic active Epstein-Barr virus infection
Epstein-Barr virus-related hemophagocytic lymphohistiocytosis syndrome
children
