摘要
目的探讨糖尿病肾病患者血清中胱抑素C(CysC)水平和意义,以及CysC在评估肾小球滤过功能中的意义。方法采用颗粒增强散射比浊法测定60例糖尿病肾病患者血清中的CysC,常规生化测定血肌肝(Scr),并以40例健康体验血清为参照组。结果糖尿病肾病患者血清CysC水平明显高于健康对照组,且敏感性显著高于Scr。结论CysC是一种能灵敏反应肾小球滤过功能的标志物,能早期发现糖尿病患者的肾脏病变。
Objective To investigate the level and the significance of the serum cystatin C(CysC) in patients with diabetic nephropathy,and the significance of the serum(CysC)in assessing the glomerular filtration function.Methods The level of the serum(CysC)and the serum creatinine(sCr) are respectively detected by endpoint nephelometry and routine biochemistry method,and compared with 40 healthy controls.Results The level of the serum(CysC)in patients with diabetic nephropathy was higher than the healthy control group,and the sensitivity of CysC was higher than the sCr.Conclusion The CysC can be a sensitive markers to reflect the glomerular filtration function,and the CysC has early diagnostic value in patients with diabetic nephropathy.
出处
《医学检验与临床》
2008年第4期49-50,共2页
Medical Laboratory Science and Clinics
关键词
糖尿病肾病
血清胱抑素C
肌酐
Diabetic nephropathy
Serum cystatin C（CysC）
Serum creatinine（sCr）
