摘要
目的分析内蒙古自治区砷中毒地区居民的主要死因,为砷中毒防治远期效应和保障居民健康提供科学依据。方法收集2016-2021年内蒙古自治区砷中毒地区居民死因资料(来自人口死亡信息登记管理系统和内蒙古自治区各盟市统计局人口信息系统),并根据是否饮用过高砷水将居民分为暴露组和非暴露组。采用SPSS 25.0软件统计分析粗死亡率(CDR)、标准化死亡率(SMR)、疾病别死亡率、死因构成比、死因顺位等。结果6年累计死亡病例9583人,年均CDR为633.12/10万,年均SMR为446.65/10万。各年份CDR随时间呈下降趋势(χ^(2)=1058.86,P<0.001)。男性CDR高于女性(χ^(2)=325.04,P<0.001)。砷中毒地区居民疾病死因以心脏病和恶性肿瘤为主,构成比分别为25.00%(2396/9583)、18.86%(1807/9583);恶性肿瘤死亡前3位依次是肺癌、肝癌、胃癌。暴露组主要疾病死因和恶性肿瘤死因的SMR均高于非暴露组(χ^(2)=147.08、26.26,均P<0.001)。结论内蒙古自治区砷中毒地区居民主要疾病死因为心脏病和恶性肿瘤,其中恶性肿瘤死亡前3位依次是肺癌、肝癌、胃癌。尽管目前全区砷中毒地区已基本实现改水,但慢性砷暴露的远期效应依然存在。
Objective To analyze the main causes of death of residents in arsenic poisoning areas of Inner Mongolia Autonomous Region,providing a scientific basis for preventing and controlling the long-term effects of arsenic poisoning and ensuring the health of residents.Methods The data on the causes of death among residents in arsenic poisoning areas of Inner Mongolia Autonomous Region from 2016 to 2021 were collected from the population death information registration management system and the population information system of various league and city statistical bureaus in Inner Mongolia Autonomous Region.Residents were divided into exposed and non exposed groups based on whether they drank high arsenic water.SPSS 25.0 software was used to statistically analyze the crude mortality rate(CDR),standardized mortality rate(SMR),disease-specific mortality rate,proportion of causes of death,and order of causes of death.Results Over the past 6 years,there was a total of 9583 deaths,with an average annual CDR of 633.12/100000 and an average annual SMR of 446.65/100000.The CDR of each year showed a decreasing trend over time(χ^(2)=1058.86,P<0.001).Male CDR was higher than female CDR(χ^(2)=325.04,P<0.001).Heart diseases and malignant tumors were the main causes of death for residents in arsenic poisoning areas,with proportions of 25.00%(2396/9583)and 18.86%(1807/9583),respectively.The top three leading causes of malignant tumor death were lung cancer,liver cancer and gastric cancer.Among residents who died from various diseases and malignant tumors,the SMR of the exposed group was higher than that of the non exposed group(χ^(2)=147.08,26.26,P<0.001).Conclusions The main causes of death of residents in arsenic poisoning areas in Inner Mongolia Autonomous Region are heart diseases and malignant tumors,with lung cancer,liver cancer,and gastric cancer being the top three leading causes of death for malignant tumors.Although the arsenic poisoning areas in the entire region have basically achieved water improvement,the long-term effects of chronic arsenic exposure still exist.
作者
崔娜
常子丽
刘一君
邓丹宇
Cui Na;Chang Zili;Liu Yijun;Deng Danyu(Department of Endemic Fluorine and Arsenic Poisoning,Inner Mongolia Autonomous Regional Center for Disease Control and Prevention(Inner Mongolia Autonomous Regional Academy of Preventive Medicine),Hohhot 010031,China)
出处
《中华地方病学杂志》
CAS
北大核心
2024年第3期219-224,共6页
Chinese Journal of Endemiology
基金
内蒙古自治区自然基金(2021MS08038、2023QN08032)
国家卫生健康委病因流行病学重点实验室(哈尔滨医科大学)开放课题(NHCKLEE20230901)
关键词
砷
暴露
死因分析
死亡率
Arsenic
Exposure
Cause of death analysis
Mortality
作者简介
通信作者:邓丹宇,Email:346379349@QQ.com
