摘要
目的 探讨中西医结合治疗慢性心力衰竭的临床疗效.方法 根据2014?年中国心衰指南临床心衰标准,纳入慢性心衰患者50例,采用随机数字表法分为两组,对照组25例,采用常规西医治疗;干预组25例,采用常规西医治疗+中药辨证论治.检测6分钟步行距离实验、明尼苏达心衰生活质量生活评分、心超测定左室射血分数(LVEF)及血浆脑钠肽(NT-proBNP)相关指标.结果 (1)6分钟步行距离实验:治疗后干预组6分钟步行距离显著高于治疗前和对照组,差异有统计学意义(P<0.05).(2)明尼苏达生活质量问卷(MLHFQ):治疗后干预组评分显著低于对照组,差异有统计学意义(P<0.05).(3)心脏超声:两组LVEF较治疗前均显著提高(P<0.05).(4)血浆NT-proBNP比较:两组治疗后均较治疗前显著降低(P<0.05),干预组较对照组显著下降(P<0.05).结论 中西医结合治疗可明显改善心力衰竭患者的临床症状及心功能.
Objective To study the clinical effect of 50 cases of chronic heart failure(CHF)treated by integrated traditional Chinese and Western medicine.Methods 50 cases of CHF were selected as the research objects,which accorded to the 2014 guidelines for heart failure in China.50 patients were randomly divided into two groups:Control group(n=25)treated with routine western medicine therapy,the treatment group(n=25)treated with routine western medicine therapy and traditional Chinese medicine therapy.The 6-minute walking distance experiment,the quality of life score of heart failure in Minnesota,the echocardiography ejection Fraction and the NT-pro-BNP were detected in the two groups.Results(1)The 6-minute walking distance experiment:the 6-minute walking distance of intervention group after treatment was significantly higher than that before treatment and control group(P<0.05).(2)Quality of life score of heart failure in Minnesota:the score of intervention group after treatment was significantly lower than that of the control group,the difference was statistically significant(P<0.05).(3)heart ultrasonic:The LVEF of the two groups were significantly higher than those before treatment(P<0.05).(4)Plasma NT-proBNP:Ther level of the two groups were significantly lower than those of before treatment(P<0.05),the intervention group was significantly lower than the control group(P<0.05).Conclusion The combined treatment of traditional Chinese medicine and Western medicine significantly improves the clinical symptoms and cardiac function of patients with heart failure.
出处
《浙江临床医学》
2019年第1期39-40,共2页
Zhejiang Clinical Medical Journal
基金
浙江省嘉兴市科技计划项目计划(2017BY18057)
上海市浦东新区卫计委项目(PW2013e-1).
关键词
中西医结合治疗
慢性心力衰竭
6分钟步行距离实验
心脏超声
血浆脑钠肽
明尼苏达生活质量问卷
Targeted traditional Chinese and Western medicine therapy
Chronic heart failure
6-minute walking distance experiment
Echocardiography
NT-pro-BNP
Quality of life score of heart failure in Minnesota
