摘要
目的分析综合康复治疗在急性脑梗死患者中的应用效果及对血清炎性因子水平的影响.方法选取2019年1—5月在该院接受治疗的122例急性脑梗死患者为研究对象,利用数字分配法分为观察组与对照组,各61例.对照组患者采用常规治疗,观察组在对照组基础上采用综合康复治疗.比较两组患者的临床疗效、治疗前后血清炎性因子水平、运动功能、神经功能、治疗后生活质量.结果观察组各项生活质量评分均高于对照组,组间差异有统计学意义(P<0.05).治疗2周、治疗1个月后,观察组患者白细胞介素-1、白细胞介素-6、超敏C反应蛋白、肿瘤坏死因子-α水平均优于对照组,组间差异有统计学意义(P<0.05).治疗2周、治疗1个月后,观察组患者的Fugl-Meyer运动功能评分、美国国立卫生研究院卒中量表评分均优于对照组,组间差异有统计学意义(P<0.05).观察组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05).结论急性脑梗死患者在常规治疗基础上应用综合康复治疗,能够提高其治疗效果,降低患者的机体炎性因子水平,改善其运动功能,值得临床推广应用.
Objective To analyze the application effect of comprehensive rehabilitation therapy in patients with acute cerebral infarction and its influence on serum inflammatory factor levels.Methods A total of 122 patients with acute cerebral infarction who were treated in this hospital from January to May 2019 were selected as the research objects,and they were divided into an observation group and a control group by using the digital allocation method,with 61 cases in each group.Patients in the control group were treated with conventional treatment,and the observation group was treated with comprehensive rehabilitation on the basis of the control group.The clinical efficacy,serum inflammatory factor levels,motor function,neurological function before and after treatment,and quality of life after treatment were compared between the two groups.Results The quality of life scores of the observation group were higher than those of the control group,and the differences between the groups were statistically significant(P<0.05).2 weeks and 1 month after treatment,in the observation group,the levels of interleukin-1,interleukin-6,high-sensitivity C-reactive protein and tumor necrosis factor-αwere better than those in the control group,the differences between the groups were statistically significant(P<0.05).2 weeks and 1 month after treatment,the Fugl-Meyer motor function assessment score and the National Institutes of Health stroke scale score of the observation group were better than those of the control group,and the difference between the groups were statistically significant(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of comprehensive rehabilitation therapy on the basis of conventional treatment for patients with acute cerebral infarction can improve the treatment effect,reduce the patient's body inflammatory factor level,and improve their motor function.It is worthy of clinical application.
作者
高磊
GAO Lei(Department of Laboratory Medicine,New Mine Laiwu Central Hospital,Jinan Shandong,271199,China)
出处
《反射疗法与康复医学》
2021年第3期146-149,共4页
Reflexology And Rehabilitation Medicine
关键词
急性脑梗死
综合康复治疗
炎性因子
治疗效果
生活质量
Acute cerebral infarction
Comprehensive rehabilitation treatment
Inflammatory factor
Treatment effect
Quality of life
作者简介
高磊(1978-),男,山东泰安人,本科,副主任技师,研究方向:临床检验。