摘要
目的探讨利培酮联合认知行为疗法治疗康复期精神分裂症的疗效.方法选取2020年1—12月该院收治的康复期精神分裂症患者98例为研究对象,按照随机数表法分为观察组49例与对照组49例.对照组患者采用利培酮治疗,观察组患者采用利培酮联合认知行为疗法治疗.对比两组患者的临床疗效、治疗前后的精神病评定量表(the brief psychiatric rating scale,BPRS)评分、日常生活质量和社会功能改善情况.结果治疗前,两组患者的BPRS评分比较,差异无统计学意义(P>0.05);治疗2、4周后,观察组患者的BPRS评分明显低于对照组,差异有统计学意义(P<0.05).治疗前,两组患者的日常生活质量和社会功能改善评分比较,组间差异无统计学意义(P>0.05);治疗后,观察组患者的日常生活质量和社会功能改善评分均明显高于对照组,组间差异具有统计学意义(P<0.05).观察组患者的治疗总有效率为95.92%,明显高于对照组的79.59%,差异具有统计学意义(P<0.05).结论利培酮联合认知行为疗法对康复期精神分裂症患者的治疗效果显著,能够有效降低患者精神病性症状的严重程度,大幅提高日常生活质量,并改善患者社会功能,值得临床推广.
Objective To explore the efficacy of risperidone combined with cognitive behavioral therapy in the treatment of schizophrenia during rehabilitation period.Methods 98 cases of schizophrenia patients admitted to the hospital during the rehabilitation period from January to December 2020 were selected for the study,and were divided into 49 cases in the observation group and 49 cases in the control group according to the random number table method.Patients in the control group were treated with risperidone and patients in the observation group were treated with risperidone combined with cognitive behavioral therapy.The clinical efficacy,the brief psychiatric rating scale(BPRS)scores,the quality of daily life and the improvement of social function before and after treatment were compared between the two groups.Results Before treatment,there was no statistically significant difference in the BPRS scores of the two groups of patients(P>0.05);after 2 and 4 weeks of treatment,the BPRS score of the observation group were significantly lower than those of the control group,and the differences betweeen the groups were statistically significant(P<0.05).Before treatment,there was no statistically significant difference between the two groups of patients’quality of daily life and social function improvement scores(P>0.05);after treatment,the improvement scores of the quality of daily life and social function of the observation group were significantly higher than those of the control group,and the difference between the groups was statistically significant(P<0.05).The total effective rate of treatment in the observation group was 95.92%,which was significantly higher than 79.59%in the control group,and the difference was statistically significant(P<0.05).Conclusion Risperidone combined with cognitive behavioral therapy has a significant therapeutic effect on patients with schizophrenia during rehabilitation period.It can effectively reduce the severity of the patients'psychotic symptoms,greatly improve the quality of daily life,and improve the social functions of patients.It is worthy of clinical promotion.
作者
李存宝
LI Cunbao(Department of Medical Treatment,Yantai Psychological Rehabilitation Hospital,Yantai Shandong,265200,China)
出处
《反射疗法与康复医学》
2021年第15期134-136,共3页
Reflexology And Rehabilitation Medicine
关键词
利培酮
认知行为疗法
康复期
精神分裂症
Risperidone
Cognitive behavioral therapy
Rehabilitation period
Schizophrenia
作者简介
李存宝(1982-),男,山东莱阳人,本科,主治医师,研究方向:精神疾病临床治疗。
