摘要
Locoregional therapy is playing an increasingly important role in the non-surgical management of hepatocellular carcinoma(HCC).The novel technique of non-thermal electric ablation by nanosecond pulsed electric field has been recognized as a potential locoregional methodology for indicated HCC.This manuscript explores the most recent studies to indicate its unique anti-tumor immune response.The possible immune mechanism,termed as nano-pulse stimulation,was also analyzed.
基金
This study was funded by the Xinjiang Key Lab Project(No.2014KL002 to X Chen)
the National Natural Science Foundation of China(No.81372425 to X Chen)
National S&T Major Project(No.SQ2018ZX100301 to X Chen)
the Zhejiang Natural Science Foundation(No.LY17H160018 to X Miao)
作者简介
These authors contributed equally to this study:Xiaobo Xu;These authors contributed equally to this study:Yiling Chen;Correspondence to:Xinhua Chen,Department of Hepatobiliary and Pancreatic Surgery,First Affiliated Hospital Zhejiang University School of Medicine,79 Qing-chun Road,Hangzhou,Zhejiang 310003,China,Tel:+86-571-87236570,Fax:+86-571-87236466,E-mail:xinhua_chen@zju.edu.cn