摘要
The first draft of the human genome,published in 2001,has had a broad effect on biomedical studies and applications.In the past two decades,the human genome project(HGP)has dramatically promoted our understanding of how genomic sequences work during development,diseases and evolution.Meanwhile,genome-editing technologies have been rapidly developed to precisely and efficiently rewrite DNA sequences of different species,especially in 2012 as the development of a revolutionary genome editing method based on clustered regularly interspaced short palindromic repeat(CRISPR)and CRISPR-associated(Cas)proteins.
作者简介
Corresponding authors:Jinsong Li,emails:jsli@sibcb.ac.cn;Corresponding authors:Anming Meng,emails:mengam@mail.tsinghua.edu.cn
