摘要
目的:探讨膈下逐瘀汤治疗乙肝肝硬化患者的临床效果。方法:采用随机法将78例乙肝肝硬化患者分为对照组和观察组,每组39例。对照组采取常规方案治疗,观察组在对照组基础上,增加膈下逐瘀汤治疗。治疗4周后,分析肝纤维化指标及T淋巴细胞亚群情况。结果:治疗后,观察组层粘连蛋白(LN)、IV型胶原(IV-C)和透明质酸酶(HA)水平均低于对照组,CD4+/CD8+、CD4+及CD3+均高于对照组,差异有统计学意义(P<0.05)。结论:膈下逐瘀汤治疗乙肝肝硬化,可改善T淋巴细胞亚群,缓解肝纤维化。
Objective:To investigate the clinical effect of Gexia Zhuyu decoction in the treatment of hepatitis B cirrhosis.Methods:78 patients with hepatitis B cirrhosis were randomized into two groups,each with 39 cases.The control group were treated with routine treatment,while the observation group were treated with Gexia Zhuyu decoction on the basis of conventional treatment.After 4 weeks’treatment,the indexes of hepatic fibrosis and T lymphocyte subsets were compared between both groups.Results:After treatment,levels of laminin(LN),collagen IV(IV-C)and hyaluronidase(HA)in the observation group were lower than those in the control group,and levels of CD4+/CD8+,CD4+and CD3+in the observation group were higher than those in the control group,which were of statistical differences(P<0.05).Conclusion:Gexia Zhuyu decoction has a good effect in the treatment of hepatitis B cirrhosis,which can improve T lymphocyte subsets and hepatic fibrosis indexes.
作者
高世钦
GAO Shiqin(Dept.of Traditional Chinese Medicine,the People’s Hospital of Xin’an County,Xin’an 471800,China)
出处
《华夏医学》
CAS
2021年第1期52-55,共4页
Acta Medicinae Sinica
关键词
膈下逐瘀汤
乙肝肝硬化
肝纤维化
T淋巴细胞亚群
Gexia Zhuyu decoction
hepatitis B cirrhosis
hepatic fibrosis
T lymphocyte subsets
作者简介
高世钦(1964—),男,河南新安人,1987年河南中医学院中医学本科毕业,现任新安县人民医院中医科副主任中医师。研究方向:肝胆脾胃疾病治疗。
