摘要
目的观察手术联合地塞米松治疗肉芽肿性乳腺炎的临床效果。方法选取2016年9月至2019年8月在郑州人民医院治疗的100例肉芽肿性乳腺炎患者,采用随机数字表法将其分为两组,每组50例。对照组采取手术治疗,观察组在外科手术治疗基础上联用地塞米松。比较两组的手术及住院时间、切除腺体量、并发症率、复发率、不良反应发生率。结果观察组患者的手术[(43.52±4.36)min]、住院时间[(8.34±2.67)d]明显短于对照组[(50.50±4.98)min,(15.46±6.50)d,P<0.05],出血量[(40.68±5.09)ml]少于对照组[(56.76±5.14)ml,P<0.05];两组患者切除腺体量比较差异未见统计学意义(P>0.05);观察组患者的并发症发生率、复发率低于对照组,但不良反应发生率高于对照组(P<0.05)。结论对肉芽肿性乳腺炎患者在外科手术治疗的基础上联用地塞米松,可提高手术效果,缩短康复时间,减少并发症及复发,但可能增加不良反应,应提高警惕。
Objective To observe the clinical effect of operation combined with dexamethasone on granulomatous mastitis.Methods From September 2016 to August 2019,100 patients with granulomatous mastitis treated in Zhengzhou People’s Hospital were divided into two groups,with 50 cases in each group.The control group was treated by operation,while the observation group was treated by dexamethasone and operation.The time of operation and hospitalization,volume of resected gland,complication rate,recurrence rate and adverse reaction rate were compared between the two groups.Results In the observation group,the operation time[(43.52±4.36)min]and hospitalization time[(8.34±2.67)d]were significantly shorter than those in the control group[(50.50±4.98)min,(15.46±6.50)d,P<0.05],and the bleeding volume[(40.68±5.09)ml]was less than that in the control group[(56.76±5.14)ml,P<0.05];there was no significant difference in the volume of resected glands between the two groups(P>0.05);the incidence of complications and recurrence rate in the observation group were lower than those in the control group group A,but the incidence of adverse reactions was higher than that of the control group(P<0.05).Conclusions The use of hormone therapy on patients based on surgical treatment can improve the surgical results,shorten the recovery time,reduce complications and recurrence,but may increase the adverse reaction rate,which should be alert to.
作者
陈晨
刘凌云
王贺
Chen Chen;Liu Lingyun;Wang He(Department of Breast Surgery,Zhengzhou People’s Hospital,Zhengzhou 450003,China;Department of Dermatology,Zhengzhou People’s Hospital,Zhengzhou 450003,China;Department of Nursing,Zhengzhou People’s Hospital,Zhengzhou 450003,China)
出处
《临床医学》
CAS
2020年第2期21-23,共3页
Clinical Medicine
基金
河南省医学科技攻关联合共建项目(2018020841).
