摘要
目的分析麻疹和风疹疑似病例的血清学检测情况,以了解麻疹、风疹病例的流行特征。方法采用酶联免疫吸附实验(ELISA)捕获法,对2014-2019年深圳市福田区麻疹、风疹疑似病例血清标本进行IgM抗体检测,结果使用SPSS 18.0软件进行统计分析。结果2014-2019年共检测麻疹、风疹疑似病例标本403份,麻疹IgM抗体阳性78份,阳性率为19.35%;风疹IgM抗体阳性51份,阳性率为12.66%。麻疹病例以8月龄~1岁婴幼儿和20~29岁成人为主,分别占麻疹总病例数的26.92%和25.64%;风疹病例以20~39岁成人和10~14岁的青少年为主,分别占风疹总病例数的52.94%和19.61%。麻疹、风疹发病时间均呈现双峰型,麻疹发病高峰在4-5月,占总病例数的44.87%,7-8月为小高峰;风疹发病高峰在4月和7月,占总病例数的43.14%。结论应提高重点人群和易感人群的疫苗接种率,加强流动人口的管理;2019年麻疹、风疹抗体阳性率明显回升,应引起重视。
Objective The aim of this research was to enhance our understanding of the epidemiological features of measles and rubella through analyzing the serological results of suspected measles and rubella cases in Futian District,Shenzhen.Methods ELISA was used to detect the IgM antibody in serum samples collected from suspected measles and rubella cases during 2014 to 2019,and statistical analysis was conducted with SPSS 18.0.Results A total number of 403 suspected samples of measles and rubella were tested.78 samples of them were positive for measles IgM antibodies,with the positive rate of measles at 19.35%.51 samples of them were positive for rubella IgM antibodies,with the positive rate of rubella at 12.66%.The majority of measles cases occurred among the group of infant and children(8 months to 1 years old),which accounted for of 26.92%of the total positive measles cases,and cases in the group of adults ranging from 20 to 29 years old accounted for 25.64%of the total positive measles cases.The majority of rubella cases occurred among the group of adults ranging from 20 to 39 years old,accounting for 52.94%of the total positive cases,and cases in the group of teenagers ranging from 10 to 14 years old accounted for 19.61%of the total positive cases.Both Measles and rubella had two peaks annually.The peak season of measles was from April to May,in which cases accounted for 44.87%of all cases,and the period from July to August had another small peak volume.Rubella’s peak season was from April to July,in which cases accounted for 43.14%of all cases.Conclusion It is necessary to increase the vaccination rate among the target group and the susceptible group,and enhance the control of immigrant population.We found that there was a significant increase of the positive rate for measles and rubella antibodies test in 2019,and such phenomenon deserves to pay closer attention to.
作者
陈润莉
张勇
张金金
曾华书
赖植发
侯红斌
CHEN Runli;ZHANG Yong;ZHANG Jinjin;ZENG Huashu;LAI Zhifa;HOU Hongbing(Shenzhen Futian District Center for Disease Control and Prevention,Shenzhen,Guangdong 518040,China)
出处
《河南预防医学杂志》
2021年第3期249-251,255,共4页
Henan Journal of Preventive Medicine
关键词
麻疹
风疹
疑似病例
IGM抗体
Measles
Rubella
Suspected cases
IgM antibody
作者简介
通信作者:陈润莉,副主任技师,本科,主要从事微生物检验工作,E-mail:chenrunli@126.com
