摘要
针对目前核医学广泛关注的医用放射性同位素99Mo/99mTc、64,67Cu、68Ge/68Ga、82Sr/82Rb、211At、225Ac等,本文利用FLUKA程序对加速器生产上述同位素的产额及产物分布进行了研究。研究表明,医用放射性同位素的产额随束流能量增加而增加,增加趋势逐渐降低;产额随辐照时间的增长而增加,随辐照后冷却时间的增长而降低,变化情况主要取决于目标医用同位素的半衰期;入射束流在同位素靶的有效射程内产生医用放射性同位素,选取合适的靶厚可以优化目标医用同位素的比活度值等;此外,束流能量越高产生的杂质核素种类及产额也相应增加,合适的辐照能区和辐照时间等,可以降低后续目标医用同位素分离纯化等工作的复杂程度。本文通过FLUKA的计算初步为加速器生产医用同位素提供了重要的依据。
The medical radioisotopes 99Mo/99mTc,64,67Cu,68Ge/68Ga,82Sr/82Rb,211At,225Ac have been attracting a lot of attention in nuclear medicine.In this paper,the yields and product distributions of the above medical radioisotopes were studied with FLUKA code.The results show that the yield growth trend becomes slower with the increase of beam energy.The yield increased with the increase of irradiation time and decreased with the increase of cooling time.The change mainly depends on the half-life of the medical radioisotopes.The incident beam produces medical radioisotopes within the effective range in the isotope target.The reasonable target thickness can optimize the specific activity value of the medical radioisotopes.Moreover,the kinds and yields of impurity nuclides also increased with the increase of the beam energy.The reasonable irradiation energy and irradiation time can reduce the complexity of subsequent medical radioisotopes separation and purification.This work provides important information for the accelerator produced medical radioisotopes by FLUKA calculation.
作者
韩瑞
陈志强
田国玉
石福栋
张鑫
刘丙岩
孙慧
HAN Rui;CHEN Zhiqiang;TIAN Guoyu;SHI Fudong;ZHANG Xin;LIU Bingyan;SUN Hui(Institute of Modern Physics,Chinese Academy of Sciences,Lanzhou 730000,China;School of Nuclear Science and Technology,University of Chinese Academy of Sciences,Beijing 100049,China)
出处
《原子核物理评论》
CAS
CSCD
北大核心
2020年第4期913-917,共5页
Nuclear Physics Review
基金
国家自然科学基金委员会-中国科学院大科学装置科学研究联合基金(U1832205)
国家自然科学基金资助项目(11875298,11605257)
作者简介
韩瑞(1985–),女,甘肃靖远人,副研究员,博士,从事原子核与粒子物理研究,E-mail:hanrui516@impcas.ac.cn;通信作者:陈志强,E-mail:zqchen@impcas.ac.cn。
