摘要
Deep brain stimulation(DBS)is considered as a treatment option for many neurological diseases.Many patients with movement disorders exhibit remarkable improvement after DBS.Owing to its minimally invasive nature,reversibility,and adjustability,DBS has been increasingly used over the past several decades.Dystonia is one of the most common movement disorders among children,and there is no effective treatment.Recently,some surgeon groups have performed DBS surgery for children.However,the outcomes of DBS in children are not well characterized.Here we mainly discuss the efficacy of DBS against childhood-onset dystonia and introduce the main procedure of pediatric DBS based on our own experience.
Deep brain stimulation(DBS) is considered as a treatment option for many neurological diseases. Many patients with movement disorders exhibit remarkable improvement after DBS. Owing to its minimally invasive nature, reversibility, and adjustability, DBS has been increasingly used over the past several decades. Dystonia is one of the most common movement disorders among children, and there is no effective treatment. Recently, some surgeon groups have performed DBS surgery for children. However, the outcomes of DBS in children are not well characterized. Here we mainly discuss the efficacy of DBS against childhood-onset dystonia and introduce the main procedure of pediatric DBS based on our own experience.
作者简介
Yongxin Wen received the B.S.degree from the First Clinical Medical College of Southern Medical University in June 2012.Now she is a M.S.candidate of the department of pediatrics,Peking University First Hospital.Her research focuses on neurological disorders of pediatrics.E‐mail:angel124@163.com,contributed equally to this work;Haibo Yang received the Ph.D.degree from the Capital Medical University in 2009.Now he is the leader of surgical group of pediatric movement disorders,Peking University First Hospital.He has a lot of experience with the diagnosis and treatment of pediatric neurosurgery disorders.He focuses on neuromodulation therapy of pediatric movement disorders,especially the operation and efficiency of DBS for early onset dystonia.E‐mail:haiboyang101@sina.com,contributed equally to this work;Xinhua Bao achieved the Ph.D.degree from Beijing Medical University in 1994.Now she is a professor of Department of pediatrics,Peking University First Hospital.She has published over 100 papers mainly focused on the pediatric neurological diseases.Her current research interests include the genetic diseases of pediatric neurology and the efficiency of DBS in early‐onset dystonia.E‐mail:zwhang@pku.edu.cn
