摘要
Deep brain stimulation(DBS)has been used as a safe and effective neuromodulation technique for treatment of various diseases.A large number of patients suffering from movement disorders such as dyskinesia may benefit from DBS.Cerebral palsy(CP)is a group of permanent disorders mainly involving motor impairment,and medical interventions are usually unsatisfactory or temporarily active,especially for dyskinetic CP.DBS may be another approach to the treatment of CP.In this review we discuss the targets for DBS and the mechanisms of action for the treatment of CP,and focus on presurgical assessment,efficacy for dystonia and other symptoms,safety,and risks.
作者简介
Corresponding author:Hongjie Jiang received his M.D.degree from the Zhejiang University School of Medicine,China(2014)and is now a neurosurgeon in the Second Affiliated Hospital of Zhejiang University,China.He has participated several national and provincial projects,including National Key R&D Plan.His current research interests focus on functional neurosurgical researches and clinical translational applications of brain–computer interface.E‐mail:insjhj@zju.edu.cn,These authors contributed equally to this work;Rui Wang received her B.S.degree from the Department of Psychology and Behavioral Sciences in Zhejiang University,China(2019).Now she is an M.D.candidate in Zhejiang University.Her current research interests focus on understanding how brain activity contributes to psychological and behavioral process.E‐mail:ruiiwang@zju.edu.cn,These authors contributed equally to this work;Zhe Zheng received his M.D.degree from Capital Medical University,China(2010)and then was employed as a neurosurgeon in the Secondary Affiliated Hospital of Zhejiang University(2011–2019).Now he is an attending neurosurgeon in functional neurosurgery.His research interests focus on deep brain stimulation and epilepsy.E‐mail:zhengzhe1982@zju.edu.cn;Junming Zhu received his Ph.D.and M.D.degree from the Department of Neurosurgery,Shanghai Medical University,China(1999),then he received his postdoctoral training in Thomas Jefferson University(2000–2001).Now he is an attending neurosurgeon in the Secondary Affiliated Hospital of Zhejiang University,China.His research focuses on epilepsy and PD.E‐mail:dr.zhujunming@zju.edu.cn
